PROSITE entry PS00511

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General information about the entry

Entry name [info]	CRF
Accession [info]	PS00511
Entry type [info]	PATTERN
Date [info]	01-JUN-1991 CREATED; 01-JUL-1999 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00442

Name and characterization of the entry

Description [info]	Corticotropin-releasing factor family signature.
Pattern [info]	[PQA]-x-[LIVM]-S-[LIVM]-x(2)-[PST]-[LIVMF]-x-[LIVM]-L-R-x(2)-[LIVMW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	42 in 42 different sequences
Number of true positive hits	35 in 35 different sequences
Number of 'unknown' hits	0
Number of false positive hits	7 in 7 different sequences
Number of false negative sequences	3
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	83.33 %
Recall (true positives / (true positives + false negatives))	92.11 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	35 sequences CRF1_CATCO (P13241), CRF2_CATCO (P25308), CRF_BOVIN (Q95MI6), CRF_CANLF (P49926), CRF_CARAU (Q9PTS1), CRF_HUMAN (P06850), CRF_MOUSE (Q8CIT0), CRF_PIG (P06296), CRF_RAT (P01143), CRF_SHEEP (P01142), CRF_XENLA (P49188), DIH41_AGRIP (C0HKT4), DIH41_BOMMO (B3IUD8), DIH45_AGRIP (C0HKT5), DIH45_BOMMO (B3IUE0), DIUH1_HYLLI (P82014), DIUH1_MANSE (P21819), DIUH1_TENMO (P56618), DIUH2_TENMO (P56619), DIUH_ACHDO (P23834), DIUH_DIPPU (P82373), DIUH_LOCMI (P23465), DIUH_MUSDO (P67800), DIUH_PERAM (P41538), DIUH_STOCA (P67801), DIUH_ZOONE (P82707), SAUV_PHYSA (P01144), UCN1_HUMAN (P55089), UCN1_MOUSE (P81615), UCN1_RAT(P55090), UTS1_CARAU (Q9PTQ4), UTS1_CATCO (P01145), UTS1_CYPCA (P01146), UTS1_ONCMY (O93448), UTS1_PLAFE (P21624) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	3 sequences DIH44_CAMFO (E2A6P1), DIUH2_HYLLI (P82015), DIUH2_MANSE (P24858)
UniProtKB/Swiss-Prot False positive sequences	7 sequences ZITB_ECO57 (Q8X400), ZITB_ECOLI (P75757), ZITB_SALTI (Q8Z8B6), ZITB_SALTY (Q8ZQT3), ZITB_SHIFL (Q83SA2), ZITB_YERPE (Q8ZGY6), ZITB_YERPS (Q66D85) » more
PDB [Detailed view]	6 PDB 2RMF; 6P9X; 6PB0; 6PB1; 7TRY; 7TS0