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PROSITE entry PS51417


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General information about the entry

Entry name [info] ARF
Accession [info] PS51417
Entry type [info] MATRIX
Date [info] 01-DEC-2008 CREATED;
10-MAY-2017 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51417
Associated ProRule [info] PRU00759

Name and characterization of the entry

Description [info] small GTPase Arf family profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=168;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=163;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-3.8837714; R2=0.0042228; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-8166.6298828; R2=18.1434937; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=2933; H_SCORE=45048; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=2459; H_SCORE=36448; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-16; D=-40; I=-40; I0=-16; B1=*; E1=*; MI=-210; MD=-210; IM=-210; DM=-210;

...
 
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-210; BD=-210;
/M: SY='S';  M=   9, -46, -24,  -7,  -3, -53, -16, -25,  10,  -6, -10,   7,  -7,  20,  -4,  29,  11,  -6,  24,  -1;
/M: SY='W';  M= -16, -40, -32,   6,   5, -20, -19,   0,  -6,  20,  20,   2,   9,  -5,  15, -14,  -8, -12,  46, -27;
/M: SY='F';  M=  -8, -44, -26,  26,  34,  -6, -16, -23,  -9,   1,   4,  -1,  29,  -1, -20,  -2,  -9, -18,   0, -30;
/M: SY='W';  M=  -2, -63, -12,  22, -60,  19,  24, -34,  26, -48, -26,   4,  -9,  33,   0,  -1,   1, -39,  45, -41;
/M: SY='K';  M=  -2, -65, -12,  23, -22, -37, -10, -51,  49, -28, -27,  12, -42,  30,  19,  10,  -3, -25, -60, -42;
/M: SY='K';  M=  -3, -72,   7,  33, -72, -49, -10, -62,  47, -58, -34,  -2,  -5,  39,  35,   2, -11, -49, -66, -47;
/M: SY='E';  M= -13, -77,  12,  62, -76, -47,  16, -67,  27, -62, -39,  34, -43,  42, -12,  -2, -14, -54, -70, -50;
/M: SY='M';  M=   4, -35, -40, -22, -15, -31,   9,  -3,  -7, -10,  59, -24, -49, -11,   6, -17,  -8,  30, -35,  40;
/M: SY='H';  M= -17,  -5,   9,  32, -66, -49,  37, -56,  22, -53,   6,  11, -41,  35,  23,   9,  25, -44, -62, -44;
/M: SY='I';  M= -36,   8, -94, -77, -33, -92, -64,  68, -74,  27,   1, -70, -80, -60, -74, -55, -29,  55, -58, -48;
/M: SY='L';  M= -25, -36, -65, -48, -25, -71, -39,  31, -45,  46,   4, -45, -27, -33, -48, -33,  22,  41, -42, -32;
/M: SY='M';  M= -30,  31, -86, -68, -24, -81, -50,  52, -63,  29,  60, -60, -70, -49, -62, -44, -22,  44, -44, -35;
/M: SY='L';  M= -43, -47, -98, -81, -25, -99, -68,  49, -78,  53,  29, -76, -84, -61, -77, -62, -36,  50, -57, -50;
/M: SY='G';  M=  -9, -41, -27, -29, -77,  85, -44, -69, -40, -73, -53, -24, -43, -30, -47,  13, -13, -48, -79, -67;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/M: SY='D';  M= -28, -82,  87,  12, -82, -45, -17, -73,  -9, -70, -48,  20, -45,  34, -26, -14,  16, -60, -79, -57;
/M: SY='N';  M= -10, -22, -16,   0, -39,  23, -13, -40,   5, -42, -21,  62, -43,   6, -14,  17,   7, -32, -55,   1;
/M: SY='A';  M=  61, -40, -29,  -8, -58, -39, -29, -42, -21, -48, -28, -18, -42, -13, -31,  51,  -8, -10, -63, -49;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/I:         I=-7; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='T';  M=  -5, -36, -36, -31, -65, -35, -39, -49, -32, -57, -37, -24, -42, -24, -39,  35,  92, -34, -70, -58;
/M: SY='T';  M=   0, -43, -27, -13, -45, -48,   8, -30, -12, -19, -16, -16, -45,  -5, -22,  21,  77, -11, -50, -37;
/M: SY='L';  M= -33, -40, -84, -66,  39, -83, -49,  46, -62,  48,  12, -60, -71, -46, -61, -45,   6,  20, -43, -34;
/M: SY='L';  M= -23, -46, -87, -70, -24, -91, -59,  23, -66,  63,  26, -66, -78, -52, -67, -54, -32,  44, -53, -45;
/M: SY='Y';  M=  -8, -63, -13,  24, -60, -50,  12, -48,  28, -33, -26,  37, -43,  10,  12,   7, -10, -39, -59,  57;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='K';  M=   0, -20, -14,   8, -56, -25, -11, -44,  42, -44,   0,   3, -43,  35,  27,   3,   0,   2, -56, -12;
/M: SY='L';  M= -27, -37, -72, -54,  30, -73, -36,  31, -50,  57,  11, -48, -63, -36, -50, -12, -19,   1, -32,  -3;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='Q';  M=  12,   8, -18,  -1, -52, -51, -13, -38,  50,  -6, -19,  -8, -44,  52, -11,   4, -10, -21, -53, -38;
/M: SY='T';  M= -16, -57,  -3,  12,   3,   0, -12, -40,  14,  -9, -20,  11, -19,   8,   0,  26,  31, -32, -54, -38;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='E';  M=  -5, -68,  -1,  38, -67,  12,   4, -56,  24, -26, -30,  30, -14,  12,   5,   3, -10, -45, -63, -25; D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='E';  M=  -9, -68,  12,  44, -67, -35,   1, -32,  14, -39, -30,   9,   4,  38,   3,  20,  -9, -23, -63, -27;
/M: SY='P';  M=  -7, -37, -24, -19,  22, -56, -20,  -6, -18,   4,  -1, -22,  36,   2, -27,  -1,  27,  25, -37, -25;
/I:         I=-8; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='E';  M= -17, -63,  11,  40, -61, -49,  26, -24,   9, -30, -26,   5, -12,  30, -10,  18,  -9,  19, -59, -42;
/M: SY='Q';  M= -10, -72,  30,  24, -72, -23,  15, -62,  30, -58, -34,  22,   8,  37,  -1,  13,  11, -49, -66, -46;
/M: SY='T';  M=  -3, -33, -44, -26, -25, -58,  14,  28, -25, -15,  47, -27, -50, -15, -31,  -2,  49,  26, -34, -23;
/I:         I=-3; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='V';  M=   4,   2, -16,  -5, -30, -56,   7,  27,  -8,  -7,  -2, -20, -48,   6,  -6,  -6,  16,  33, -38, -26;
/M: SY='P';  M= -13, -48, -17, -10, -61, -42,   5, -51, -13, -53, -32, -13,  92,  -7, -23,  22,   6, -39, -64, -49;
/M: SY='T';  M= -11,   0, -37,  -7, -52, -43, -31, -29, -23, -40, -23, -23, -46, -17, -30,  -9,  92, -21, -59, -46;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='V';  M= -16, -28, -59, -40,  -6, -61, -27,  33, -14,   4,  34, -36, -53,  -1, -39, -22,   9,  51,  31, -19;
/M: SY='G';  M= -20, -55, -15, -12, -71,  79, -28, -60,   1, -62, -42, -15, -47, -10,  -1, -14, -19, -48, -70, -56;
/M: SY='F';  M=  -7, -15, -15,  -8,  31, -23,   4,  -6,  -8,  -4,  -1,  -9,  -8,   2, -11,   6,   2,  -4, -14,  -8;
/M: SY='N';  M= -17,   1,   0,  11, -59, -49,  12, -46,   2, -47, -25,  76, -43,  17, -12,  23,   2, -20, -58, -41;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='V';  M=  -6,   2, -53, -35, -21, -60, -26,  32, -10,   6,  40, -32, -52,   0, -36,  -2,   6,  43, -31, -20;
/M: SY='E';  M=  -9, -63, -12,  54, -60, -27, -11, -28,  25, -48, -26,  -4, -43,  10,  16,  -7,  26,  -1, -59, -42;
/M: SY='T';  M=  -2, -10,  12,  22, -62, -49, -10, -34,  33, -49,   7,  23, -15,  11,   6,  -6,  42, -40, -60, -42;
/M: SY='V';  M= -39, -44, -96, -79,  16, -94, -63,  55, -75,  36,   9, -72, -81, -59, -74, -57, -32,  56, -53, -44;
/M: SY='E';  M= -17, -65,   4,  30, -63, -49,   9, -36,  22, -24, -27,  10,  19,  19,   8,   9,  26,  -9, -61, -42;
/M: SY='Y';  M=   0, -37, -36, -11,   9, -56, -20, -14,   7,  14,  -1, -21, -48,  13, -19,  -5,  24,  20, -37,  32;
/I:         I=-4; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='K';  M= -18, -70,  14,  20, -69,  20, -10, -59,  37, -56, -33,  -1, -22,  36,  19,  14, -11, -47, -64, -45; D=-4;
/I:         I=-4; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='N';  M= -20, -75,  30,  16, -75, -22,  13, -65,  32, -61, -37,  64, -42,  24, -12,  15,  -5, -52, -69, -49;
/M: SY='V';  M=   8, -31, -47, -29,  26, -59, -23,   6, -27,  15,  21,  -2, -51,  -1, -10,  -6,   5,  27, -32,  13;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='Q';  M= -17, -66,  -3,  27, -64, -49,  14, -16,  24, -51, -28,  -3, -42,  40,  16,  25,  36, -32, -61, -43;
/M: SY='F';  M= -39, -45, -94, -76,  56, -91, -56,  35, -71,  46,  41, -69, -77, -53, -69, -53, -32,  29, -45, -38;
/M: SY='T';  M=  -4, -64,   6,  14, -37, -49,  22, -50,  26, -32,   8,  32, -42,  28, -10,  10,  38, -29, -60, -42;
/I:         I=-11; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='V';  M= -16, -38, -86, -68,  26, -83, -50,  44, -64,  29,  43, -61, -71, -48, -62, -45, -24,  52, -44, -35;
/M: SY='W';  M= -22, -37, -53, -36,  29, -64, -19, -12,  -6,   3,  -1, -33, -56, -21, -11, -25, -15,  -9, 125,  28;
/I:         I=-10; MI=0; MD=-52; IM=0; DM=-52;
/M: SY='D';  M= -37, -97,  95,  48, -96, -44, -22, -88, -20, -84, -65,   4, -48,  -3, -41, -21, -33, -75, -92, -67;
/I:         I=-9; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='I';  M= -42, -46, -98, -81, -26, -98, -68,  59, -78,  43,  40, -76, -83, -62, -77, -61, -35,  50, -57, -50;
/M: SY='G';  M=   5, -38, -28, -24, -70,  75, -36, -57, -29, -61, -40,   0, -41, -20, -38,   9,   7, -25, -73, -61;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='G';  M= -15, -52,   6,  -6, -72,  76, -28, -62, -19, -63, -43, -10, -44, -10, -15,   8, -15, -47, -74, -58;
/M: SY='Q';  M=  -2,  -3,  11,   5, -62, -24,  18, -51,   3, -50, -27,  -4, -23,  84, -11,  14, -10, -40, -60, -43;
/I:         I=-9; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='E';  M= -11, -65,  14,  40, -21, -31,  -9, -40,  27, -25,   3,  16,   7,  31,  -9,   0,  -9, -42, -60, -42; D=-9;
/I:         I=-9; DM=-45;
/M: SY='K';  M=  -7, -70, -11,  16, -69, -50, -10, -58,  44, -44, -31,  33,  -6,  18,  36,  19,  -2, -46, -64, -45; D=-9;
/I:         I=-9; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='M';  M= -19, -29, -67, -48,  30, -24, -31,  33, -44,  40,  42, -42, -56, -30, -44, -27, -12,   2, -29,  20;
/M: SY='R';  M= -26, -66, -26,  -8, -66, -28, -13, -53,  14, -51,   2, -13, -49,  26,  86,  -8, -18, -44, -60, -47;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='S';  M=  -1, -61, -12,  18,  -6, -25, -11, -46,  19, -46, -24,  14,  25,  10,   0,  43,   5, -37, -58, -41;
/M: SY='M';  M=  -7, -28, -56, -37,   5, -61, -26,  22, -17,  23,  48, -34, -52, -22, -37,  -1,  14,  10, -30,  42;
/M:
/M: SY='E';  M= -18, -73,  18,  40, -73, -38,  11, -63,  39, -59, -34,  14,  -2,  27,  13,  25, -11, -50, -67, -47;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='N';  M= -17,  -5,   3,  22, -66, -49,  36, -55,  15, -53,   2,  38, -41,  32,  27,  21,   9, -44, -62, -44;
/M: SY='Y';  M= -65, -68, -83, -76,  51, -94,  10, -48, -71, -37, -34, -54, -83, -49, -68, -58, -58, -49,  15, 119;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='Y';  M= -16,  44, -35, -41,  31, -62, -27,   7, -38,   5,   8, -36, -53, -25, -39, -22,   6,  12, -28,  72;
/M: SY='Q';  M=  13, -68, -10,  31, -67, -27,  14, -39,  13, -53, -30,  17, -24,  42,  25,  24, -10, -32, -63, -44;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='N';  M= -11, -29,  -4,  42, -67,  10, -10, -56,  13, -40, -31,  43, -42,  27,   7,  16, -10, -45, -63, -44;
/I:         I=-3; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='T';  M=  16,  42, -44, -29, -42,  -1, -30, -27, -28, -33, -14, -25, -44, -18, -35,  28,  55,  19, -50, -38;
/M: SY='Q';  M= -17, -14,  40,  20, -68, -48,  45, -57,  16, -37, -31,  18, -41,  49,   5,   2,  -2, -46, -63,  -5;
/M: SY='G';  M=  27, -39, -34, -17, -10,  43, -22,  -5, -17, -15,  -7, -20, -47,  -8, -27,   1,  -9,  12, -44, -31;
/M: SY='I';  M= -15, -42, -89, -72, -11, -90, -59,  53, -69,  44,   6, -67, -78, -55, -69, -53, -29,  50, -53, -44;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='I';  M= -42, -45, -99, -84, -35,-101, -75,  74, -81,   8,  16, -79, -87, -68, -82, -65, -35,  64, -67, -57;
/M: SY='F';  M= -48, -53, -86, -74,  86, -87, -11, -27, -69,   8, -14, -53, -76, -47, -65, -49, -41, -16,  51,  76;
/M: SY='V';  M= -27, -38, -67, -51, -29, -73, -44,  19, -47,  -5,  51, -48, -14, -36, -51, -35, -20,  76, -47, -37;
/M: SY='V';  M= -41, -45, -98, -81, -31, -98, -70,  56, -78,  27,  27, -76, -85, -64, -78, -62, -34,  68, -61, -53;
/M: SY='D';  M= -36, -90, 101,  11, -89, -45, -23, -82,   2, -80, -62,   0, -48,  -5, -38, -22, -32, -70, -87, -64;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='S';  M=  35,  35, -51, -40, -63, -32, -42, -47, -39, -54, -34, -28, -40, -29, -45,  80,  -5, -31, -69, -58;
/M: SY='S';  M=  28, -44, -26,  -2, -53, -44, -22, -38, -12, -31, -22, -15, -43,  -5, -24,  59,  41, -19, -57, -43;
/M: SY='D';  M= -18, -81,  89,  18, -80, -30,  19, -70,  -8, -68, -46,   2, -45,   4, -25,   6, -21, -58, -77, -39;
/M: SY='R';  M= -10, -65,  -2,  34, -62, -49,  12, -15,  17, -43, -27,  -3,   2,  19,  49,  -7,  -2,  -7, -60, -42;
/M: SY='E';  M=   5, -68,  21,  50, -67, -49, -10, -56,  11, -10, -30,  11, -42,  30,   1,   4,  10, -34, -63, -44;
/I:         I=-7; MI=0; MD=-38; IM=0; DM=-38;
/M: SY='R';  M= -29, -75,   7,  -2, -77, -56, -12, -64,  31, -60, -38,  -9, -49,  24,  85, -18, -21, -54, -66, -52;
/M: SY='M';  M= -32,  11, -87, -68,  16, -82, -49,  33, -64,  55,  64, -61, -70, -47, -61, -44, -25,   9, -40, -33;
/M: SY='E';  M=   0, -68,   9,  54, -67, -31, -10, -56,   5, -29, -31,   6,  22,  33, -10,  11,  -5, -28, -63, -44;
/M: SY='E';  M=  11, -59,  -4,  55, -55, -25, -12, -30,   9, -22, -22,  -5, -43,  25, -12,  -7,  13, -20,  24, -39;
/M: SY='S';  M=  31,  26, -40, -23, -31, -53, -24,  -6, -22, -11,  10, -24, -48, -12, -30,  45,  18,  13, -40, -28;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='K';  M= -13,  -3, -17,   1, -63, -14, -11, -50,  59, -49, -28,  -7, -44,  16,  45,   7, -12, -31, -59, -43;
/M: SY='E';  M=  -7, -68,   9,  43, -67, -24, -10, -18,  18, -54, -30,  35, -41,  43,  -3,  -6,   6, -14, -63, -44;
/M: SY='E';  M=   3, -62, -11,  65, -59, -50, -12, -13,   3, -47, -25,  -5, -43,  41, -11,  -8,  14, -38, -59, -10;
/M: SY='L';  M= -52, -57,-100, -82,  21,-103, -65,  14, -78,  75,  40, -79, -86, -58, -76, -67, -44,  -5, -48, -40;
/M: SY='H';  M= -11, -61,  13,  17, -36, -50,  65, -46,  19, -28,  -6,  -4, -42,  36,  -5,   2,  15, -36,  23,   3;
/M: SY='K';  M= -17, -70,   0,  28, -69, -27,  28, -59,  38, -45, -11,  26, -41,  23,  18,  28,   1, -47, -64, -45;
/M: SY='M';  M= -11, -42, -87, -69, -24, -87, -56,  48, -66,  47,  51, -64, -75, -51, -66, -50, -28,  39, -49, -41;
/M: SY='L';  M= -31, -40, -75, -58, -22, -80, -47,  31, -54,  61,  34, -54, -69, -41, -56, -24, -13,  23, -45, -36;
/M: SY='Q';  M=   6, -68,  29,  17, -31, -29,  -9, -57,  15, -54,  -4,  28,  -9,  36,  17,  14,   2, -32, -63, -44;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='H';  M=   0,  -1,   0,   0,  -1,  -1,   1,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,  -1,  -1,  -1; D=-5;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='E';  M=   0,  -1,   0,   1,  -1,  -1,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,  -1,  -1,  -1; D=-5;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='Q';  M=   3, -69,  23,  25, -68, -47,  16, -58,  12, -38, -32,  12,  13,  47,  26,   0,  -9, -46, -63, -44; D=-5;
/I:         I=-5; DM=-24;
/M: SY='L';  M= -19, -33, -53, -36, -23, -63, -29,  32, -33,  38,  25,   8, -55, -22, -37, -13, -12,  26, -36, -25; D=-5;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='Q';  M=  24,  17,  -4,  14, -53, -49, -11, -40,  21, -32, -20,  -5, -42,  43, -11,  23,  -8, -23, -54, -38; D=-5;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='G';  M= -17, -67,  14,  16, -38,  35, -10, -55,  14, -53, -29,  27, -17,  26,   7,  -1,   8, -25, -62, -44;
/I:         I=-4; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='V';  M=  17, -37, -36, -19, -29, -57, -21,  24,  14,   9,  -2, -22, -49,  -9, -10,   5,   7,  28, -38, -26;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='P';  M= -13, -47, -22, -11, -53, -45,   0, -27, -11, -44, -24, -14,  87,  -5, -21,  30, -10, -21, -57, -42;
/M: SY='V';  M= -13, -40, -88, -71,  10, -87, -56,  54, -67,  28,   5, -65, -75, -53, -67, -50, -27,  57, -51, -41;
/M: SY='L';  M= -35, -44, -78, -61, -13, -82, -44,   4, -55,  67,  13, -56, -70, -42, -55, -44, -28,  31,  31, -24;
/M: SY='V';  M= -27, -36, -76, -58,  -8, -35, -46,  60, -55,  -3,  18, -53, -68, -43, -57, -39, -20,  62, -46, -35;
/M: SY='L';  M= -22, -33, -65, -47,  28, -68, -30,  -2, -43,  56,  10, -42, -13, -30, -45, -29, -15,  18,   8,  -1;
/M: SY='A';  M=  67, -38, -37, -21,  -5, -17, -23, -20, -20, -25,  -8, -22, -48, -11, -28, -13, -10, -14,  28, -25;
/M: SY='N';  M= -24, -62,  -3,  -5, -76, -14, -30, -72, -22, -73, -54, 107, -48, -13, -33, -16, -24, -57, -76, -59;
/M: SY='K';  M= -26,   4, -25,  -7, -63, -55,  23, -52,  84, -51, -31, -13, -49,   6,   5, -17, -18, -43, -58, -44;
/M: SY='Q';  M= -19, -60, -17,   0, -56, -52, -12,  -8,  15, -44,  22,   2, -44,  86,  13,   5, -11, -35, -56, -40;
/M:
/M: SY='L';  M= -12, -38, -38, -20, -29, -58, -21,   3,  22,  41,  21, -22, -50,  11, -11, -17, -10,  18, -38, -26;
/I:         I=-4; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='P';  M= -13, -59,  -3,  24, -58, -44,  -9, -27,  28, -35, -25,  -3,  47,  18,   7,  19,  -9, -38, -55, -39; D=-4;
/I:         I=-4; DM=-23;
/M: SY='D';  M=   0,  -1,   0,   0,  -1,   0,   0,  -1,   0,  -1,   0,   0,   0,   0,   0,   0,   0,  -1,  -1,  -1;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='A';  M=   3,   0,  -1,   0,  -2,  -2,  -1,  -1,   0,  -2,  -1,  -1,  -1,   0,   0,   1,   0,  -1,  -2,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='M';  M= -10, -31, -49, -31, -20, -59,   3,   9, -28,  35,  72, -30, -51, -18,  -5, -20,  -9,   5, -31,   2; D=-3;
/I:         I=-3; DM=-17;
/M: SY='S';  M= -12, -66,  18,  19, -65, -22,  12, -54,  10, -35,  -2,  34, -25,  11,  -2,  42,  23, -43, -61, -43; D=-3;
/I:         I=-3; DM=-17;
/M: SY='M';  M=  20, -17, -28,  18, -34, -53, -17,   5, -11, -10,  29, -16,  22,  -3,  -8,   3,   9,  16, -41, -28; D=-3;
/I:         I=-3; DM=-17;
/M: SY='Q';  M=  27,  10,  -4,  24, -55, -36, -11, -43,  14, -36, -22,   6,  -4,  36, -12,  10,  11,  -5, -55, -39; D=-3;
/I:         I=-3; DM=-17;
/M: SY='E';  M= -29, -87,  60,  72, -85, -36, -17, -77,   7, -73, -51,   3, -44,  15, -26,  -3, -23, -64, -81, -58; D=-3;
/I:         I=-3; DM=-17;
/M: SY='I';  M= -42, -45, -98, -81, -28, -98, -69,  74, -78,  29,  36, -76, -84, -63, -78, -62, -35,  44, -59, -52; D=-3;
/I:         I=-3; DM=-17;
/M: SY='T';  M=  -6, -39, -12,   8, -36, -36,   8,  15,  22, -28, -13,  -6, -31,  16,   0,  18,  23,  -7, -37, -26; D=-3;
/I:         I=-3; DM=-17;
/M: SY='Q';  M= -12, -71,  32,  40, -71, -47,   6, -61,  32, -57, -34,  13, -40,  42,  11,   5,  14, -36, -65, -46; D=-3;
/I:         I=-3; DM=-17;
/M: SY='Y';  M=  10,  -6, -27,   5,  -2, -53, -17, -12,  21,   1,  17,  -4, -46,   7,  10,   4,  -3,   0, -41,  26; D=-3;
/I:         I=-3; DM=-17;
/M: SY='L';  M= -49, -53,-100, -82,  38,-100, -64,  24, -78,  68,  44, -78, -83, -58, -75, -64, -41,  -5, -47, -40; D=-3;
/I:         I=-3; DM=-17;
/M: SY='N';  M=   0,   0,   0,   0,  -1,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='L';  M=   0,   0,   0,   0,   0,  -1,   0,   0,   0,   1,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='H';  M=   0,   0,   0,   0,  -1,   0,   1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='K';  M=   0,  -1,   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='L';  M=   0,   0,  -1,   0,   0,  -1,   0,   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='Q';  M=   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='N';  M=   0,   0,   0,   0,  -1,   0,   0,  -1,   0,  -1,   0,   1,   0,   0,   0,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='E';  M=   1,  -3,   1,   1,  -3,  -1,   0,  -2,   0,  -2,  -1,   0,  -2,   1,   0,   0,   0,  -2,  -3,  -1; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='R';  M=   0,   0,   0,   0,  -1,   0,   0,  -1,   0,  -1,   0,   0,   0,   0,   1,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='N';  M=   0,   0,   0,   0,  -1,  -1,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-3;
/I:         I=-3; DM=-17;
/M: SY='W';  M= -15,  48, -57, -39, -18, -59, -26,  13, -35,  -9,  23, -34, -13, -23, -37,   0,   1,  15, 113,  -5; D=-3;
/I:         I=-3; DM=-17;
/M: SY='H';  M= -16,  32, -13,   0,   4, -52,  65,  -6,   3, -18, -12, -11, -44,  32,  17,  11,  -9, -22, -46,  -2; D=-3;
/I:         I=-3; DM=-17;
/M: SY='I';  M= -27,  31, -82, -64,   0, -77, -46,  58, -60,  25,   4, -56, -67, -46, -59, -40,  -1,  47, -42, -32; D=-3;
/I:         I=-3; DM=-17;
/M: SY='Q';  M= -16,  -8, -21,  21,   4, -52,  11, -18,  -5,  -1, -12,  -2, -44,  67,  -3, -11,  -9, -11, -46,  16; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='P';  M=  33, -50, -17,   8, -61,  11, -20, -49,  -9, -51, -29, -10,  53,  -1, -21,  32,   7, -38, -62, -47;
/M: SY='C';  M=   0,  90, -55, -39, -28, -53, -31,  33, -36, -18,  -2, -34, -50, -25, -40,  13,  36,   4, -39, -28;
/M: SY='C';  M= -14,  76, -11, -15, -42, -49, -22, -29, -16, -34, -15,  -6, -46,  -7, -26,  69,  -9, -22, -49,  -5;
/M: SY='A';  M=  63,  21, -56, -39, -31, -61, -34,  24, -36,   4,  -2, -36, -56, -26, -42, -23,   0,  12, -43, -32;
/M: SY='L';  M=  -3, -39,  -4, -15, -32, -55, -19,  17,  10,  32,  -4, -19, -47,  -6,  -5, -15,  25,  16, -39, -27;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='T';  M= -17, -61,  13,  25, -17, -50, -11, -16,  14, -32, -24,   4, -43,   9,  14,  10,  56, -36, -57, -40; D=-6;
/I:         I=-6; DM=-33;
/M: SY='G';  M= -18, -59, -13,   7, -57,  56, -14, -45,  16, -46,   6,  16, -44,   6,  -3,   7, -11, -26, -58, -42; D=-6;
/I:         I=-6; DM=-33;
/M: SY='E';  M=  -4, -68,  36,  46, -66, -49,  36, -55,  14, -12, -30,  -2, -42,  24, -10,  -6,   4, -31, -62,  -5; D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='G';  M=  -7, -61,  -6,  10, -67,  59, -17, -55,  -5, -55, -34,  37, -15,   3,  -5,   3,  -5, -44, -66, -49; D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='L';  M= -37, -44, -86, -69, -27, -88, -58,  55, -65,  56,   7, -65, -77, -52, -66, -51,  10,  28, -53, -45; D=-6;
/I:         I=-6; DM=-33;
/M: SY='K';  M=  -1, -61,  27,   9, -58, -50, -11, -26,  33, -46,   5,  -5,   9,  26,   3,  -7,  -9,  12, -57,  24; D=-6;
/I:         I=-6; DM=-33;
/M: SY='E';  M=  -7, -71,  32,  52, -70, -26,  19,   1,  19, -57, -33,   5, -32,  37, -10,   0, -11, -48, -65, -46; D=-6;
/I:         I=-6; DM=-33;
/M: SY='G';  M=  25, -49,  -4,  -5, -50,  44, -17, -12,  -7, -39, -19, -11, -44,   1,  -9,   8,  18, -12, -54, -39; D=-6;
/I:         I=-6; DM=-33;
/M: SY='L';  M= -14, -35, -80, -61,  33, -75, -40,  23, -56,  56,  41, -53, -64, -40, -54, -37, -20,   7,  32, -25; D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='Q';  M=  -6, -72,  20,  34, -72, -48, -10, -62,  23, -58, -34,  30, -41,  48,  26,  18,   0, -49, -66, -16; D=-6;
/I:         I=-6; DM=-33;
/M: SY='W';  M= -20, -51,  -7,  -8, -43, -55, -16, -31,  13, -17, -15, -14, -47,  31,  -2,  -2, -12, -25, 132, -33;
/M: SY='L';  M= -34, -45, -73, -55, -20, -81, -46,  20, -17,  69,  51, -53, -69, -38, -51, -43, -27,  -1, -45, -36;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='I';  M=  14,  -2, -42, -14, -26, -58,  -5,  32, -23,  13,   1,  -7, -50,  10, -20,  13,  16,  13,   0,  -5;
/M: SY='N';  M=  19, -72,  17,  23, -71, -38,  28, -61,  24, -58, -34,  49, -42,  36, -10,  21, -11, -32, -66, -47;
/M: SY='Q';  M=   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   1,   0,   0,   0,   0,  -1,   0;
/M: SY='I';  M=   2, -30, -65, -47,  17, -66, -33,  43, -43,  33,   6, -42, -58, -30, -45,  11,  -4,  29, -34, -23;
/I:         E1=0; IE=-210; DE=-210;
» more

Post-processing [info]

COMPETES_HIT_WITH PS51418; PS51419; PS51420; PS51421; PS51422; PS51423; PS51424

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 188 in 188 different sequences
Number of true positive hits 184 in 184 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 97.87 %
Recall (true positives / (true positives + false negatives)) 99.46 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo, L_Cerutti
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 184 sequences 

AR13A_HUMAN (Q5H913), AR13A_MOUSE (Q9D416), AR13A_RAT   (Q6AXT3), 

AR13B_DANRE (Q8JHI3), AR13B_HUMAN (Q3SXY8), AR13B_MOUSE (Q640N2), 
AR8BA_DANRE (Q6NZW8), ARF11_CAEEL (Q94231), ARF12_CAEBR (Q61LA8), 
ARF12_CAEEL (Q10943), ARF1_ARATH  (P36397), ARF1_BOVIN  (P84080), 
ARF1_BRARP  (Q96361), ARF1_CATRO  (O23778), ARF1_CHLRE  (P51821), 
ARF1_DAUCA  (P51822), ARF1_DICDI  (O00909), ARF1_DROME  (P61209), 
ARF1_HUMAN  (P84077), ARF1_LOCMI  (P61210), ARF1_MACFA  (Q4R5P2), 
ARF1_MOUSE  (P84078), ARF1_ORYSJ  (Q06396), ARF1_PLAF7  (Q7KQL3), 
ARF1_PLAFA  (Q94650), ARF1_PLAFO  (Q25761), ARF1_RAT(P84079), 
ARF1_SALBA  (O48649), ARF1_SCHPO  (P36579), ARF1_SOLTU  (P51824), 
ARF1_XENLA  (P51643), ARF1_YEAST  (P11076), ARF2A_ARATH (Q9LQC8), 
ARF2B_ARATH (P0DH91), ARF2_BOVIN  (P84081), ARF2_MOUSE  (Q8BSL7), 
ARF2_ORYSJ  (P51823), ARF2_RAT(P84082), ARF2_YEAST  (P19146), 
ARF3_ARATH  (P40940), ARF3_BOVIN  (Q5E9I6), ARF3_HUMAN  (P61204), 
ARF3_MOUSE  (P61205), ARF3_PONAB  (Q5R5P7), ARF3_RAT(P61206), 
ARF3_TAKRU  (P61207), ARF3_YEAST  (P40994), ARF4_ARATH  (Q9SHU5), 
ARF4_BOVIN  (Q3SZF2), ARF4_DROME  (P40945), ARF4_HUMAN  (P18085), 
ARF4_MOUSE  (P61750), ARF4_PONAB  (Q5RCF1), ARF4_RAT(P61751), 
ARF4_XENLA  (P51644), ARF5_ARATH  (Q9ZPX1), ARF5_CHICK  (P49702), 
ARF5_HUMAN  (P84085), ARF5_MOUSE  (P84084), ARF5_RAT(P84083), 
ARF6_CHICK  (P26990), ARF6_DROME  (P40946), ARF6_HUMAN  (P62330), 
ARF6_MOUSE  (P62331), ARF6_PIG(Q007T5), ARF6_RAT(P62332), 
ARF6_SCHPO  (Q9Y7Z2), ARF6_XENLA  (P51645), ARFD_DICDI  (Q54I24), 
ARFF_DICDI  (Q54HK2), ARFH_DICDI  (Q54JJ3), ARFJ_DICDI  (Q54V47), 
ARFK_DICDI  (Q54V41), ARFL_DICDI  (Q54YV7), ARFRP_BOVIN (Q32LJ2), 
ARFRP_HUMAN (Q13795), ARFRP_MOUSE (Q8BXL7), ARFRP_PONAB (Q5R579), 
ARFRP_RAT   (Q63055), ARF_AJECA   (P34727), ARF_CANAL   (P22274), 
ARF_CRYNB   (P0CM17), ARF_CRYNJ   (P0CM16), ARF_DUGJA   (P91924), 
ARF_ENCCU   (Q8SQH8), ARF_EREGS   (Q75A26), ARF_GIAIN   (P26991), 
ARF_MAIZE   (P49076), ARF_NEUCR   (Q7RVM2), ARF_VIGUN   (O48920), 
ARL10_HUMAN (Q8N8L6), ARL10_MOUSE (Q9QXJ4), ARL11_BOVIN (Q58DI9), 
ARL11_HUMAN (Q969Q4), ARL11_MOUSE (Q6P3A9), ARL11_RAT   (Q5BK71), 
ARL13_CAEEL (H2L0N8), ARL13_CHLRE (A8INQ0), ARL14_HUMAN (Q8N4G2), 
ARL14_MOUSE (Q3SXC5), ARL15_BOVIN (Q5EA19), ARL15_HUMAN (Q9NXU5), 
ARL15_MOUSE (Q8BGR6), ARL15_PONAB (Q5RFN0), ARL16_HUMAN (Q0P5N6), 
ARL17_HUMAN (Q8IVW1), ARL1_BOVIN  (Q2YDM1), ARL1_CAEEL  (Q20758), 
ARL1_DROME  (P25160), ARL1_HUMAN  (P40616), ARL1_MOUSE  (P61211), 
ARL1_RAT(P61212), ARL1_YEAST  (P38116), ARL2_BOVIN  (Q2TA37), 
ARL2_CAEBR  (Q627K4), ARL2_CAEEL  (Q19705), ARL2_DICDI  (Q54UF1), 
ARL2_DROME  (Q06849), ARL2_HUMAN  (P36404), ARL2_MOUSE  (Q9D0J4), 
ARL2_RAT(O08697), ARL3_BOVIN  (Q2TBW6), ARL3_CAEEL  (O45379), 
ARL3_CHLRE  (A8ISN6), ARL3_DANRE  (Q1MTE5), ARL3_HUMAN  (P36405), 
ARL3_MOUSE  (Q9WUL7), ARL3_PIG(Q52NJ4), ARL3_PONAB  (Q5RCQ6), 
ARL3_RAT(P37996), ARL3_TAEGU  (B5FYQ0), ARL3_XENLA  (Q8QHI3), 
ARL3_YEAST  (Q02804), ARL4A_BOVIN (Q3T0M9), ARL4A_HUMAN (P40617), 
ARL4A_MOUSE (P61213), ARL4A_RAT   (P61214), ARL4C_HUMAN (P56559), 
ARL4C_MOUSE (P61208), ARL4D_BOVIN (Q0VC18), ARL4D_HUMAN (P49703), 
ARL4D_MOUSE (Q99PE9), ARL4D_PONAB (Q5REU3), ARL5A_BOVIN (Q2KJ96), 
ARL5A_HUMAN (Q9Y689), ARL5A_MOUSE (Q80ZU0), ARL5A_RAT   (P51646), 
ARL5B_HUMAN (Q96KC2), ARL5B_MOUSE (Q9D4P0), ARL5C_HUMAN (A6NH57), 
ARL5C_MOUSE (Q6P068), ARL5_CAEEL  (P34212), ARL5_DICDI  (Q55AD9), 
ARL6_BOVIN  (Q0IIM2), ARL6_CAEBR  (Q60Z38), ARL6_CAEEL  (Q18510), 
ARL6_DANRE  (Q5M9P8), ARL6_HUMAN  (Q9H0F7), ARL6_MOUSE  (O88848), 
ARL6_PONAB  (Q5R4G5), ARL8A_ARATH (Q8VY57), ARL8A_CHICK (Q5ZKQ8), 
ARL8A_HUMAN (Q96BM9), ARL8A_MOUSE (Q8VEH3), ARL8A_XENTR (Q6P8C8), 
ARL8B_ARATH (Q93Y31), ARL8B_BOVIN (Q2KI07), ARL8B_HUMAN (Q9NVJ2), 
ARL8B_MACFA (Q4R4S4), ARL8B_MOUSE (Q9CQW2), ARL8B_PONAB (Q5R6E7), 
ARL8B_RAT   (Q66HA6), ARL8C_ARATH (Q8W4C8), ARL8D_ARATH (F4IZ82), 
ARL8_DICDI  (Q54R04), ARL8_DROME  (Q9VHV5), ARL9_HUMAN  (Q6T311), 
ARLX_DICDI  (Q1ZXA5), ARL_SCHPO   (Q09767), CIN4_YEAST  (P39110), 
TRI23_CAEEL (Q09654), TRI23_HUMAN (P36406), TRI23_MOUSE (Q8BGX0), 
TRI23_RAT   (P36407)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

MGLA_MYXXD  (Q1DB04)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			4 sequences
			


			
SAR1_ENCCU  (Q8SS09), SRPRB_HUMAN (Q9Y5M8), SRPRB_MOUSE (P47758), 

			
SRPRB_RAT   (Q4FZX7)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			110 PDB
			


			1E0S; 1FZQ; 1HUR; 1J2J; 1KSG; 1KSH; 1KSJ; 1MOZ; 1MR3; 1O3Y; 1R4A; 1R8Q; 
			
				1R8S; 1RE0; 1RRF; 1RRG; 1S9D; 1U81; 1UPT; 1YZG; 1Z6X; 1Z6Y; 1ZD9; 1ZJ6; 
				2A5D; 2A5F; 2A5G; 2AL7; 2B6H; 2H16; 2H17; 2H18; 2H57; 2J59; 2J5X; 2K5U; 
				2KSQ; 2W83; 3AQ4; 3BH6; 3BH7; 3DOE; 3DOF; 3LRP; 3LVQ; 3LVR; 3N5C; 3O47; 
				3PCR; 3TJZ; 3VHX; 4C0A; 4DCN; 4FME; 4GOJ; 4GOK; 4HMY; 4ILE; 4KAX; 4M9Q; 
				4Q66; 4ZI2; 4ZI3; 5A1U; 5A1V; 5A1W; 5A1X; 5A1Y; 5DE3; 5DI3; 5EE5; 5J5C; 
				5NZR; 5NZS; 5NZT; 5NZU; 5NZV; 6BBP; 6BBQ; 6CM9; 6CRI; 6D83; 6D84; 6DFF; 
				6FAE; 6II6; 6PTA; 6VBV; 6VOA; 7DN8; 7DN9; 7MGE; 7OK7; 7R4H; 7URO; 7UX3; 
				7XRD; 8D4C; 8D4D; 8D4E; 8D4F; 8D4G; 8D9R; 8D9S; 8D9U; 8D9W; 8EZJ; 8F6D; 
				8P50; 8SDW
			
			

			» more