PROSITE entry PS51522
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General information about the entry
| Entry name [info] | ZF_NANOS |
| Accession [info] | PS51522 |
| Entry type [info] | MATRIX |
| Date [info] |
01-FEB-2011 CREATED;
10-MAY-2017 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51522 |
| Associated ProRule [info] | PRU00855 |
Name and characterization of the entry
| Description [info] | Zinc finger nanos-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=55; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=50; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.4555142; R2=0.0061741; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8011.4443359; R2=2.1657834; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=818; H_SCORE=9783; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=494; H_SCORE=9081; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-49; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='C'; M= -76, 77, -84, -81, 11, 23, 57, -8, 41, -79, -76, -74, -90, -78, -75, 4, 6, 24, -92, 15; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /M: SY='W'; M= -12, 50, -77, 2, -78, 27, -78, -81, -6, -85, -81, 43, -89, -75, 6, 7, -2, 13, 73, 43; /M: SY='Y'; M= -90, -94, -96, -93, 92, -99, -71, 4, -82, -18, -66, -90,-100, -87, 26, -87, -83, -71, -58, 93; /M: SY='C'; M= -79, 154, -99, -99, -87, -95, -99, 1, -95, -83, -83, -85,-108,-102,-101, -82, -79, -78,-116, -97; /M: SY='Y'; M= -6, -95, -83, 22, 24, -93, -72, -77, 3, 9, 34, -83, -92, -70, 62, -81, -81, -79, 54, 71; /M: SY='H'; M= -73, -91, 19, 7, -87, 29, 57, -95, 38, -93, -84, 35, -84, -67, -70, 45, 6, -91, -94, 26; /M: SY='N'; M= -9, -88, -72, -73, -81, -81, -73, -80, 57, -86, -79, 64, 18, -70, -67, -3, 42, 4, -90, 43; /M: SY='G'; M= 3, 29, -75, 9, -89, 65, -76, -97, 29, -93, -84, 7, -86, 41, -1, -69, -79, -92, -87, 32; /M: SY='E'; M= -78, 46, -71, 68, 15, -92, -76, -76, -74, 35, -70, -80, -86, 16, -79, 11, 15, -76, -86, 33; /M: SY='Q'; M= -2, -93, -70, 51, -92, -83, -74, -84, -69, -16, 45, 18, 55, 62, -75, 24, -1, -83, -96, -85; /M: SY='R'; M= 26, -91, -78, -2, 21, -3, -75, -87, 10, -83, 44, 18, 6, 13, 63, 0, -75, -84, -90, -77; /I: I=-12; MD=-30; /M: SY='E'; M= 22, 48, 29, 67,-108, -93, -88,-106, -80,-103, -99, -82, 18, -75, -89, 6, -83, -98,-111,-101; D=-12; /I: I=-12; MD=-30; /M: SY='I'; M= -11,-106, -96, 21, 4,-109, -99, 43, -84, -82, -82, -96,-102, -88, 42, -92, -4, 14,-106, -89; D=-12; /I: I=-12; MD=-30; /M: SY='W'; M= -1,-100,-100, -94, 6, -98, -83, -71, 6, -4, -74, -97,-102, -88, -87, -89, -87, 29, 100, 85; D=-12; /I: I=-12; MD=-30; /M: SY='Q'; M= 10, -96, -80, 13, -96, -85, 47, -92, -73, -24, 28, -76, -90, 66, 10, 53, -76, -89,-102, -84; D=-12; /I: I=-12; MI=0; MD=-30; IM=0; DM=-30; /M: SY='S'; M= -66, -84, 13, -74, -92, 22, 27, -90, -75, -93, -86, 16, -82, -71, -81, 81, 57, -84,-103, -83; /M: SY='H'; M= -87, -99, 21, -68, -87, -88, 149,-104, -75, -87, -73, -59, -87, -65, -70, -76, -84,-103,-121, -56; /M: SY='C'; M= -73, 73, 9, -78, -89, -6, 47, -80, -78, -86, -81, 51, 18, -77, -84, 41, 35, 20,-108, -84; /M: SY='C'; M= -82, 88,-100, -94, 16,-101, -89, 52, -87, 45, 45, -91, -98, -88, 15, -88, -79, -7, -92, -73; /M: SY='K'; M= -80, -95, -77, -66, 2, -88, -72, -93, 82, -90, -81, -70, -86, -60, 75, 11, -76, -90, -85, 22; /M: SY='D'; M= -16, -94, 74, 1, -94, -6, -75, -98, 59, -97, -90, 42, -84, -67, -66, -4, -74, -95, 70, -82; /I: I=-20; MD=-50; /M: SY='P'; M= 10, -98, 29, 25,-102, 13, -81,-100, 37, -99, -91, -74, 42, -70, 40, 3, -79, -95,-100, -92; D=-20; /I: I=-20; MI=0; MD=-50; IM=0; DM=-50; /M: SY='D'; M= -88,-102, 70, 26,-105, -91, -78,-105, 35,-104, -97, 35, -91, -71, 36, -78, 5,-101,-112, -93; D=-20; /I: I=-20; DM=-50; /M: SY='G'; M= -70, -98, -86, -97,-104, 103, -92,-112, -91,-107, -96, -71, -89, -88, -98, -70, -89,-105, -95, -99; D=-20; /I: I=-20; DM=-50; /M: SY='D'; M= -81, -96, 44, 3, 2, -4, -82, -85, 25, -10, -83, -74, 9, -74, 36, 9, 6, -3, -99, -83; D=-20; /I: I=-20; DM=-50; /M: SY='V'; M= -75, -88,-100, -96, -75,-103,-102, 9, -93, 6, -63, -94, -97, -95, -96, -83, 36, 87,-106, -82; D=-20; /I: I=-20; DM=-50; /M: SY='W'; M= -5, -90, -91, -90, -79, -93, -97, 43, -87, -74, -74, -82, -88, -88, -92, -6, 78, 25, 85, -78; D=-20; /I: I=-20; DM=-50; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /M: SY='P'; M= -83,-107, 19, 23,-103, -86, -84, -93, -77,-101, -89, -84, 122, -78, -89, -80, -77, -97, -98, -99; /M: SY='H'; M= -79, -91, -87, -81, -75, -97, 80, 50, 49, 12, -62, -80, -90, -77, -73, -83, -76, 51, -98, -72; /M: SY='L'; M= -84, -87,-102, -94, -59,-102, -84, -50, -94, 91, 57,-100,-100, -87, -91, -94, -80, -57, -89, -70; /M: SY='W'; M= -6, -94, -82, -71, 43, -85, -77, -89, 40, -85, -80, -74, -89, 40, 70, 32, -76, -87, 73, -68; /M: SY='R'; M= 16, -90, -72, 4, 20, -80, -73, -91, 40, -89, -82, 41, -86, 14, 60, 38, -71, -86, -91, -78; /M: SY='Y'; M= -82, 38, -85, -81, -60, -93, 62, 20, -79, -3, 46, -80, -93, 53, -78, -78, 15, -71, -72, 92; /M: SY='V'; M= 2, -86, -85, -77, -81, -90, -86, -4, 43, -70, 34, -78, -87, 20, 0, -72, 47, 62, -98, -80; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /M: SY='P'; M= -79,-101, 51, 4,-101, 36, -78, -99, 12, -99, -89, -71, 78, 21, 39, -74, -79, -97, -97, -90; /M: SY='H'; M= -81, 38, -92, -89, 12, -99, 77, 58, -83, -8, -62, -84, -95, -83, 15, -85, -77, 49, -92, 16; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /I: I=-26; MD=-65; /M: SY='G'; M= -73, -97, -77, 22,-102, 81, 27,-106, 24,-102, -91, -70, -86, 12, -79, 0, -83,-101, -96, -91; D=-26; /I: I=-26; MI=-65; MD=-65; IM=-65; DM=-65; /M: SY='A'; M= 95, -82, -84, -80, -96, -69, -87, -86, -81, -89, -82, 9, -87, -78, -86, 3, -71, -74, -97, -91; D=-26; /I: I=-26; DM=-65; /M: SY='T'; M= -73, -84, -78, -79, -89, -88, -85, -82, -71, -86, -81, -68, -82, -77, 36, -1, 107, -74,-106, -85; D=-26; /I: I=-26; DM=-65; /M: SY='G'; M= 2, -93, -82, -92,-100, 103, -88,-106, -87,-102, -91, -68, -86, -84, -94, -66, -84, -98, -91, -95; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='D'; M= 0, -94, 73, 58, 16, -86, 27, -94, 44, -90, -87, -65, -81, -65, -68, -72, 5, -89, -98, -79; /M: SY='Q'; M= -82, -93, 54, -65, 14, -86, -70, -80, 44, 8, 45, 46, -88, 60, -67, -75, -76, -83, -89, 14; /M: SY='A'; M= 83, -82, -79, -79, -94, 33, -83, -88, -79, -90, -83, 25, -84, -75, -84, 31, -69, -77, -95, -89; /M: SY='H'; M= -87, -99, -71, -71, -85, -89, 153,-104, -76, -86, -71, -60, -87, -65, -70, -76, -85,-103,-121, -54; /M: SY='T'; M= -71, -81, -76, -78, -84, -87, 57, -74, -76, -79, -75, -65, -79, -78, -82, -56, 112, -3,-107, -79; /M: SY='E'; M= -80, -94, 18, 50, -79, -93, -80, 49, -6, -14, -72, -77, 36, -72, -2, -75, 42, -68, -91, 26; /M: SY='K'; M= 21, -87, -78, -70, -87, -82, -79, -83, 72, 3, -76, -70, -83, -66, 28, 32, 40, -79, -94, -82; /M: SY='Y'; M= -86, -99, -81, 8, -48, -95, 67, 19, 0, -72, -68, -82, -94, -73, -75, -82, -82, -76, -58, 119; /M: SY='C'; M= -80, 149, -93, -93, -88, -93, 73, -97, -91, -86, -84, -80,-105, -94, -94, -81, -80, -86,-119, -89; /M: SY='P'; M= -84,-105, 41, -70, -98, -86, -84, -87, -80, -7, -84, -83, 120, -82, -91, -81, -77, -92, -99, -96; /M: SY='M'; M= -81, -93, -80, 14, -76, -92, -73, 4, 50, 13, 85, 6, -88, 16, 38, -80, -77, -72, -88, 15; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 12 in 12 different sequences |
| Number of true positive hits | 12 in 12 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | ZN_FING |
| Feature description [info] | Nanos-type |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
12 sequences
NANO1_DANRE (E7FDB3), NANO1_HUMAN (Q8WY41), NANO1_MOUSE (Q80WY3), NANO1_XENBO (Q90ZZ5), NANO1_XENLA (Q07937), NANO1_XENTR (Q90ZZ6), NANO2_HUMAN (P60321), NANO2_MOUSE (P60322), NANO3_DANRE (Q90WW1), NANO3_HUMAN (P60323), NANO3_MOUSE (P60324), NANOS_DROME (P25724)» more
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| PDB [Detailed view] |
3 PDB
3ALR; 5KL1; 5KL8 |