PROSITE entry PS51678
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General information about the entry
| Entry name [info] | SAM_MT_PRMT |
| Accession [info] | PS51678 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2013 CREATED;
01-JUL-2013 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51555 |
| Associated ProRule [info] | PRU01015 |
Name and characterization of the entry
| Description [info] | SAM-dependent methyltransferase PRMT-type domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=313; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=313; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2801752; R2=0.0087699; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=3161; N_SCORE=30.0; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=482; N_SCORE=6.5; MODE=1; TEXT='RR'; /DEFAULT: M0=-39; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='D'; M= 13, -90, 50, 29, -15, -20, 16, -19, -21, 11, -76, 32, -86, 6, -14, 7, -73, -27, -98, -80; /M: SY='Q'; M= -1, -93, 4, 51, -90, -45, -75, -77, 9, -10, 14, -10, -84, 66, 20, -25, -75, 19, -96, -82; /M: SY='D'; M= 8, -93, 39, 37, -85, -84, -75, -6, -70, -21, -78, 17, 38, 17, 12, 16, -73, -4, -94, 14; /M: SY='Y'; M= -22, -97, -86, -81, -63, -88, -74, -14, -13, 0, -73, -11, 61, -1, -17, 0, -12, -79, 81, 86; /M: SY='F'; M= 16, -88, -18, -82, 64, -32, 60, -70, -81, 29, 13, -1, -93, -6, -8, -14, -18, -26, -83, -12; /M: SY='Q'; M= -29, -94, 26, 39, -10, -17, -73, -89, 7, -88, -82, -69, -11, 69, 32, 12, 6, -30, -91, -2; /M: SY='P'; M= -28, -4, -76, 22, -23, -29, 20, -90, -73, -91, 6, -74, 80, -71, 7, 65, -69, -88, -94, -8; /M: SY='Y'; M= -23, 23, 8, 2, 19, -94, 55, -68, -83, 22, -66, -82, -94, -79, -83, -81, -20, 13, -72, 91; /M: SY='C'; M= -8, 102, 8, 2, -16, 11, -82, -87, -22, -83, 56, -72, -89, -77, -84, 57, -70, -82,-100, -85; /M: SY='D'; M= -20, -91, 75, -14, -89, 7, 65, -87, -20, -38, -83, -6, -84, -72, -79, -3, 43, -20,-104, -11; /M: SY='C'; M= -21, 83, -83, -89, 21, -25, -75, 13, -81, -6, -72, 60, -97, -82, -9, -78, -77, -37, 36, 71; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='D'; M= -74, -92, 67, -71, -89, 51, -79, -14, -32, 10, -80, -66, -86, -1, -18, 33, 6, -83, -99, -85; /M: SY='W'; M= -28, -92, -8, -24, -8, -21, -79, 25, -85, 42, 35, -87, -93, 17, -86, -83, -20, -6, 64, 60; /M: SY='H'; M= -9, -93, -71, -72, -84, -83, 134, -96, -73, -87, -74, 20, -87, -10, -16, 7, 7, -94,-107, 4; /M: SY='Q'; M= -80, -93, -79, 15, 11, -90, 12, 1, -73, 32, 20, -7, -90, 75, -26, 9, -77, -73, -80, 52; /M: SY='E'; M= 15, -89, -65, 78, -87, -87, -77, -23, -23, -1, 18, -17, -79, -3, -75, -68, 57, -75, -97, -84; /I: I=-28; MD=-70; /M: SY='Y'; M= -99,-109, 3,-100, -77,-110, -93, 0,-101, 27, -78, 13,-112, -8,-102,-100, -94, 10, 39, 55; D=-28; /I: I=-28; MD=-70; /M: SY='S'; M= 15,-113,-105, -28,-112,-106,-108, -29, -16, -11,-101, -11, -8,-100,-106, 18, -11, -99,-123,-111; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='M'; M= -82, -91, -88, 11, 58, -93, 20, -65, -79, -58, 121, -84, 24, 41, -79, -84, -79, -71, -84, -62; /M: SY='E'; M= -79, 11, -78, 61, -71, -98, -83, 23, -80, 58, 33, -88, -89, -74, -84, -14, -77, 4, -94, -78; /M: SY='N'; M= -21, 24, -69, -70, -14, -80, 53, -91, 32, -39, -80, 79, -88, 36, 39, -5, -17, -89, -99, -78; /M: SY='D'; M= -82, -97, 113, -5,-100, -83, -73, -17, -72, -94, -93, -56, -84, 7, -80, -11, -74, -25,-115, -86; /M: SY='W'; M= 1, -93, -82, -19, -14, -1, -79, -79, 22, -32, 18, -77, 32, 36, 12, 25, -16, -3, 63, 19; /M: SY='V'; M= -77, -90, 25, 18, -3, -97, -88, 22, -22, -6, -67, -83, 8, -80, 6, -81, -7, 69, -98, -78; /M: SY='R'; M= -84, -99, -78, -9, -86, -93, -69, -97, 48, -91, -81, -73, -90, -58, 104, -78, -81, -92, -86, 32; /M: SY='N'; M= -77, -86, -67, -80, -73, 3, -67, -83, -73, -85, 3, 91, -87, -74, -79, -63, 67, -82, -86, 70; /M: SY='D'; M= -7, -93, 71, 10, -94, -10, -76, -3, 45, -38, -82, -6, -84, 41, -68, -11, -27, -29,-100, -84; /M: SY='Q'; M= 27, -90, -80, -69, -14, -33, -77, -81, 53, -12, 9, -73, -85, 53, 39, -2, 15, -25, -91, -79; /M: SY='Y'; M= -88, -98, -7, -12, 23, -96, -59, 3, -83, -70, -68, -87, -98, -79, -81, -84, -82, -75, -51, 128; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='R'; M= -82, -96, -16, -18, 10, -29, -2, -78, -9, 23, -70, -77, -92, 65, 68, -78, -81, -25, -83, 41; /M: SY='D'; M= 26, -91, 53, 23, -94, -79, 12, -91, -65, -24, -82, 49, -85, 42, 35, 14, -72, -87,-101, -83; /M: SY='A'; M= 81, -83, -85, -12, 1, -11, -82, -74, -81, -78, -75, -81, -87, -78, -85, -14, -72, 21, -84, 43; /M: SY='I'; M= -79, -88, -98, -95, -10,-102, -93, 58, -93, 55, -53, -1, -97, -91, -94, -88, -75, 57, -93, -73; /M: SY='Q'; M= -80, -94, -6, 40, 44, -92, -74, -14, 3, 0, 29, -77, -88, 51, 25, 1, -77, -24, -82, 28; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='Q'; M= 8,-107, -90, 2,-102, -33, 27, -98, -3, 1, -87, -87,-100, 58, 29, -85, -11, -96,-108, -93; D=-24; /I: I=-24; DM=-60; /M: SY='N'; M= 25, -96, -15, -89, -94, -89, -4, -15, -25, -14, 34, 65,-100, -86, -91, -22, -13, -6,-112, -93; D=-24; /I: I=-24; DM=-60; /M: SY='K'; M= -87,-104, -15, 3,-101, -95, 50, -98, 72, -98, -88, -77, 37, 24, 12, -82, -84, -22, 18, -86; D=-24; /I: I=-24; DM=-60; /M: SY='H'; M= 14, -90, 26, -28, -27, -82, 80, -89, 31, -89, -80, 36, 2, -68, 26, -21, 30, -30,-102, -76; /M: SY='A'; M= 49, -87, 34, 2, -24, -85, 3, 22, -23, 19, -68, -79, -89, -77, -19, -32, -73, 28, -96, -79; /M: SY='F'; M= -76, -88, -18, -22, 57, 21, -83, 8, 6, 25, -70, -10, -89, -80, -82, 35, 22, -71, -85, -68; /M: SY='K'; M= 28, -91, -69, 42, -96, -82, -75, -92, 60, -91, -82, -18, -9, 51, 3, 3, 23, -85, -94, -85; /M: SY='D'; M= -74, -93, 67, 5, -96, 45, -77, -92, 5, -41, -88, 16, 17, -4, -78, 30, -73, -21,-101, -88; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='K'; M= 11, 10, -82, -75, -80, -84, -81, -20, 56, 10, -72, -74, -86, -72, -15, 37, 34, 12, -92, 3; /M: SY='H'; M= -76, -90, -86, -83, -78, -31, 94, 12, -82, -32, -66, -78, 24, -81, -18, -77, 28, 67,-105, -73; /M: SY='V'; M= -73, 16, -98, -92, -71,-101, -99, 39, -90, -4, -59, -92, -95, -1, -92, -83, -7, 90,-101, -78; /M: SY='L'; M= -3, 49,-100, -92, -62, -97, -83, -54, -92, 77, 69, -95, -98, -86, -90, -88, -79, -21, -89, 2; /M: SY='D'; M= -79, 15, 94, -16, -86, -90, -81, -67, -79, 3, -77, -67, -89, -79, -86, -77, -8, 54,-110, -84; /M: SY='V'; M= -24, -86,-101, -95, -68,-101, -99, 51, -93, 25, -56, -96, -96, -93, -95, -86, -72, 84, -98, -77; /M: SY='G'; M= -18, -92, -82, -90, -97, 98, -87, -23, -86, -98, -89, -68, -85, -82, -92, 23, -80, -92, -92, -93; /M: SY='C'; M= 48, 82, 52, 27, -94, -4, -83, -90, -77, -89, -85, -70, -84, -76, -84, -65, 49, -80,-104, -90; /M: SY='G'; M= -68, -95, 18, -88,-101, 103, -87,-108, -86,-104, -93, -66, -86, -84, -93, -67, -85,-102, -93, -95; /M: SY='T'; M= -69, 23, -77, -76, -3, -80, -79, -86, -67, -86, -82, -67, -83, -71, 52, 71, 75, -79, -98, -80; /I: I=-45; MD=-115; /M: SY='G'; M= -76,-101, -92,-101,-103, 91, -95,-106, -95, -37, 17, -78, -95, -92,-101, -12, -91,-103,-100,-100; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='I'; M= -84, -94, -99, -92, 24,-101, -92, 73, -93, 50, -56, -95, 62, -90, -96, -90, -78, -53, -87, -72; /M: SY='L'; M= -84, -87,-102, -94, -58,-104, -87, 3, -96, 93, -46,-101,-101, -88, -93, -95, -80, -55, -89, -71; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='S'; M= 21, -86, -78, -77, -93, 27, -81, -23, -76, -92, -85, -68, 26, -71, -13, 89, -62, -82, -97, -87; /M: SY='M'; M= -81, 13,-100, -93, -16,-100, -85, 14, -91, 67, 90, -94, -96, -86, -90, -89, -13, 12, -91, -71; /M: SY='M'; M= -3, -89, -96, -87, 81, -92, -80, -9, -21, 11, 87, -87, -94, 20, -18, -26, -79, -67, 30, -56; /M: SY='A'; M= 82, 65, -85, -80, -89, -73, -87, 5, -18, -81, -77, -11, -87, -78, -84, 21, -69, -23, -97, -88; /M: SY='A'; M= 78, -83, -83, -18, -86, -75, 12, 4, -22, -11, -73, -78, -86, -75, -19, 25, -69, -3, -95, -83; /M: SY='K'; M= 10, -94, -76, -19, -91, -86, 53, 17, 65, -84, -76, -70, -85, 42, 50, -12, -18, -80, -94, -78; /M: SY='A'; M= 66, -85, -79, 39, -80, -80, -81, -17, -78, 19, 55, -80, -85, -72, -82, 5, -7, -68, -92, -16; /I: I=-24; MD=-60; /M: SY='G'; M= -10, -92, -84, -91, -91, 87, -85, -94, -86, -40, 36, -72, -88, -82, -92, 23, -20, -90, -91, -1; D=-24; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='A'; M= 79, -82, -82, -78, -88, -73, -83, -75, -76, -34, -76, 19, -23, -75, 5, 19, -6, 17, -97, -86; /M: SY='K'; M= -40, -95, 36, -13, -97, -20, -75, -98, 86, -96, -86, -66, -9, -61, 47, 3, -75, -93, -95, -84; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='K'; M= -6, -2, -15, -67, 11, -84, 30, -91, 68, -87, 5, -69, -86, 24, 43, 32, -74, -87, 36, -74; /M: SY='V'; M= -72, 11,-101, -95, 0,-102, -99, 9, -93, -7, 11, -95, -97, -94, -94, -85, -70, 96,-100, -75; /M: SY='Y'; M= -81, -92, -90, -90, 18, -95, -72, 37, -82, -8, -64, -85, -94, -82, -9, -12, 36, 10, -66, 99; /M: SY='A'; M= 86, 24, -87, -81, -86, -73, -88, 20, -82, -14, -73, -80, -86, -79, -87, 12, -12, -65, -94, -85; /M: SY='V'; M= -75, 68,-100, -96, -68,-101, -95, 34, -93, 18, 21, -94, -98, -93, -94, -86, -73, 80, -98, -3; /M: SY='E'; M= -78, -98, 37, 106, -95, -91, -70,-100, -61, -94, -90, -71, -75, -55, -71, -17, -77, -94, -96, 6; /M: SY='K'; M= 48, -2, -80, -73, -92, 1, -83, -82, 54, -38, -80, -14, 51, -20, -70, 3, -17, -5, -95, -87; /I: I=-38; MD=-97; /M: SY='N'; M=-100,-112, -96,-106, 37, 0, 19,-111,-102,-108,-105, 53,-115,-100,-106, 25, -94,-111,-109, -7; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='S'; M= -5, -90, -3, 44, -92, -79, -73, -89, 18, -18, -82, 45, 16, -3, 14, 51, -19, -86, -99, -86; /M: SY='P'; M= -12, -96, 9, 31, -5, -84, -77, -26, 17, -90, -83, 33, 78, 23, -7, -72, 19, -86, -96, -85; /M: SY='M'; M= 10, -87, -84, -83, -3, -20, 22, 5, -80, -28, 111, 32, -88, 1, -81, 31, -72, -68, -93, -72; /M: SY='A'; M= 78, -86, -86, -79, -84, -28, 13, -1, -71, -48, -75, -80, -88, -74, 50, -67, -74, -4, 18, -3; /M: SY='D'; M= -22, -94, 52, 5, -14, -88, 37, 1, 27, -81, -77, -9, -87, 38, 30, -75, -27, 15, -93, 19; /M: SY='C'; M= -2, 77, -89, -83, -70, -91, 43, -12, -79, 31, 27, -82, -94, 21, 7, -22, 7, -5, -88, 46; /M: SY='A'; M= 69, -83, -91, -84, 21, -81, -82, -67, -84, 34, 63, -84, -89, -81, -86, -70, 19, -65, -86, 4; /M: SY='R'; M= -31, 12, -74, 54, -4, -6, 8, -28, -26, 13, -9, -78, -87, -66, 70, -78, -28, -28, -93, -78; /M: SY='K'; M= 22, -90, -28, 32, -90, -82, 9, -85, 64, 0, -77, 16, -83, 20, -14, 19, -72, -35, -95, -82; /M: SY='I'; M= -82, -91, -92, -92, 13, -98, -84, 74, -19, 27, 12, 29, -94, -85, -18, -86, -76, 14, -84, 31; /M: SY='V'; M= 30, -86, -94, -88, 14, -90, -90, 44, -83, -61, 52, -86, -91, -84, 9, -12, -16, 61, -93, -74; /M: SY='K'; M= -8, -91, 19, 19, -19, -85, 42, -23, 53, -47, -78, 35, -85, -1, 14, -21, 7, 1, -98, -79; /M: SY='H'; M= 44, -89, 4, -23, 8, -29, 57, -13, 16, -47, 35, -10, -87, 16, -16, 2, -74, -24, -90, 8; /M: SY='N'; M= -79, -87, -4, 4, -90, -72, -62, -93, -65, -97, -86, 116, -89, -2, -13, -19, -15, -94,-104, 6; /M: SY='G'; M= -74, 17, 17, -75, -96, 66, 13, -96, 13, -41, -86, 50, 15, 27, -78, -20, -14, -94, -98, -88; /M: SY='W'; M= -85, -92,-106, -95, 48, -98, -91, -58, -92, 58, 64,-100, -98, -89, -91, -94, -84, 9, 118, -57; /M: SY='E'; M= 32, -88, 35, 49, 5, -28, -76, -90, 10, -89, -85, 3, -81, -3, -74, 38, 24, -83, -96, -82; /M: SY='D'; M= -31, -93, 86, -14, -97, -4, 35, -18, 5, -95, -89, 71, -86, -69, -13, -70, -73, -92,-109, -85; /I: I=-29; MD=-75; /M: SY='K'; M= -86,-100, 38, -72, -94, -94, 10, 22, 50, -86, -81, 21, -92, 20, 41, -80, -33, 6,-104, -86; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='V'; M= -76, -89,-101, -96, -5,-104,-100, 73, -91, -5, -57, -94, -95, -92, -21, -87, -73, 77, -95, -74; /M: SY='T'; M= -75, -89, -67, 49, -15, -87, 29, -82, 31, -84, -79, 17, -81, 28, -15, -10, 69, -2, -98, -80; /M: SY='V'; M= -78, -88,-102, -96, 36,-103, -93, 48, -94, 39, -56, -96, -98, -93, -94, -89, -75, 69, -87, 5; /M: SY='I'; M= -39, 24,-101, -97, 31,-103, -96, 84, -94, 18, -57, -94, -12, -93, -96, -89, -76, 26, -87, -13; /M: SY='H'; M= -77, -93, -11, 45, -15, -20, 60, -93, 42, -29, -81, 15, 4, -13, 25, 35, -73, -90, -96, -78; /I: I=-45; MD=-115; /M: SY='K'; M= -30, 9, -10, 6,-100, 50, -84, -99, 52, -96, 35, -73, -88, -16, -73, 30, -79, -94,-100, -92; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='D'; M= -80, 10, 61, -62, -95, -24, 9, -95, 57, -91, 29, -65, -24, 9, 58, 5, -76, -91, -99, -82; /M: SY='M'; M= -1, -85, -90, -85, -75, -86, -84, 8, -18, 7, 82, -82, -7, -79, -84, 49, -68, 51, -96, -77; /M: SY='E'; M= -76, -92, 10, 72, -92, -89, 10, -90, -61, -39, -82, -69, -79, 8, 44, -11, 65, -84,-100, -83; /M: SY='D'; M= -77, -93, 75, 52, -18, -83, 11, -92, 6, -36, -86, -1, -81, 8, -73, 25, 23, -89,-103, -82; /M: SY='W'; M= -82, -92, -7, -92, -10,-101, -96, 55, -93, 47, -58, -95, -12, -90, -94, -90, -79, 43, 95, -68; /I: I=-28; MD=-70; /M: SY='T'; M= -27,-103, 11, -32,-110, -95, -92,-104, 15,-106, -98, -80, -9, 43, -85, 37, 45, -98,-114, -99; D=-28; /I: I=-28; MD=-70; /M: SY='P'; M= -26,-118,-109,-106,-112, -1,-112, 16, -3,-102, -99, -11, 19, -9,-106, -27, -99, 8,-122,-111; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='D'; M= 13, -97, 44, 35, -89, -92, 37, 16, -80, 16, -77, 31, -93, -77, -16, -81, -81, -37,-106, -86; D=-28; /I: I=-28; DM=-70; /M: SY='M'; M= -10, -95, -86, -11, -12, -5, -81, 0, 9, 20, 51, -83, 45, 51, -79, -79, -16, -35, -89, 3; D=-28; /I: I=-28; DM=-70; /M: SY='P'; M= -9, -96, -15, 16, -12, -4, 20, -83, -11, -30, -81, -79, 93, -76, -13, -74, 22, -16, -96, -85; /M: SY='E'; M= 11, 10, 12, 70, -89, -5, -1, -22, -10, -89, -84, -73, 18, -2, 10, 0, -76, -86, -91, 24; /M: SY='K'; M= -21, -95, -16, -63, -91, -86, -73, -92, 72, -40, -80, -69, -9, 56, 58, 3, -17, -88, -90, -2; /M: SY='V'; M= 50, -86, -93, -87, -79, -86, -95, 49, -87, -66, -66, -88, 37, -86, -91, -12, -70, 64, -97, -83; /M: SY='D'; M= -80, -93, 108, -55,-100, -79, -71, -98, -72, -99, -95, 47, -84, -71, -80, 4, 26, -94,-116, -87; /M: SY='I'; M= -41, -90, -96, -91, -69,-101, 56, 69, -14, 33, -56, -89, -94, -86, -88, -86, -75, 53, -96, -73; /M: SY='I'; M= -81, 18,-102, -96, -64,-103, -91, 68, -94, 59, 58, -96, -96, -89, -94, -91, -77, 19, -92, -73; /M: SY='V'; M= -77, -88,-103, -97, 32,-103, -99, 56, -94, 9, -58, -96, -96, -95, -95, -88, -74, 78, 48, -68; /M: SY='S'; M= 33, -82, -76, -77, -92, 27, -81, -90, -77, -92, -86, -65, -82, -71, -82, 90, 24, -81, -98, -86; /M: SY='E'; M= -78, -99, -50, 114, -99, -94, -72, -16, -60, -91, -88, -75, -73, -52, -70, -75, -78, -89, -97, -90; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='W'; M= -84, -95,-101, -94, 44, 1, -92, 21, -91, 45, -64, -95, 10, -90, -93, -88, -19, -24, 117, 10; /M: SY='M'; M= -80, -87, -96, -89, 40, -95, -80, -56, -87, 56, 98, -89, -12, -5, -86, -15, 8, -21, -86, -66; /M: SY='G'; M= -71, -93, 61, 12,-100, 78, -79,-103, -78,-100, -93, 3, -84, -75, -86, 20, -14, -97, -99, -91; /M: SY='Y'; M= 30, -84, -78, -80, -73, -18, -75, -79, -78, -83, -78, -3, -85, -74, -82, 63, 55, -16, -83, 68; /M: SY='M'; M= -34, 26, -87, 37, 70, 6, -83, 34, -84, -8, 82, -86, -90, -81, -87, -84, -80, -65, -81, -63; /M: SY='L'; M= -80, -88, -90, -12, -67, 38, -84, -59, -89, 79, 13, -2, -96, -84, -90, -85, -81, -66, -90, -76; /M: SY='P'; M= -83, 17, 46, -78, 8, -93, -86, 36, -85, 33, -67, -82, 73, -85, -91, -82, 12, -24, -95, -79; /M: SY='W'; M= -81, 24, -81, -88, 39, 43, -6, -90, -80, -88, -85, 71, -94, -81, -24, -76, -82, -94, 124, 14; /M: SY='E'; M= -78, -98, 19, 102,-101, -20, 14,-101, -61, -94, -89, 1, -76, 32, -70, -73, -78, -95, -99, -88; /I: I=-38; MD=-97; /M: SY='N'; M= -81, -97, -79, -89, -30, 36, 19,-101, -82, -31, -93, 69, -97, -81, 1, 47, -78, -99,-109, -92; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='M'; M= 26, -89, -92, -83, -2, -90, 9, -19, -74, 35, 96, -85, -92, -6, 45, -81, -78, -66, -87, 2; /M: SY='F'; M= -78, -88, -92, -89, 61, -21, -84, 33, -88, 45, -61, -84, -94, 6, -88, 45, -74, -21, -80, 0; /M: SY='W'; M= -80,-100, 49, 35, -89, -6, -83, -27, -75, -31, -86, -75, 77, -74, -19, 8, -8, -89, 88, -82; /M: SY='S'; M= -71, -89, -14, 48, -77, -81, -75, -25, -16, -4, -78, -71, -83, -67, -77, 72, 23, -79, 34, 45; /M: SY='C'; M= -79, 87, 16, -24, -10, -97, -84, -25, -89, 26, -65, -87, -98, -88, -90, -84, -76, 58, -86, 59; /M: SY='L'; M= -81, -90, -87, 9, -69, -99, -82, 17, -22, 66, -57, -13, -94, -7, 39, -86, -78, 17, -92, -76; /M: SY='H'; M= -81, -94, 54, 10, -23, -87, 85, -26, 9, -84, -78, -9, -86, 7, -73, -25, 29, -33, 41, 50; /M: SY='A'; M= 77, -83, -85, -82, -86, 31, -86, -75, -81, 9, -74, -11, -87, -79, -20, -14, -72, 3, -94, -86; /M: SY='R'; M= 21, -91, -89, -80, -76, -92, 52, -15, -9, 39, -65, -82, -93, -73, 64, -80, -78, 24, 35, -74; /I: I=-24; MD=-60; /M: SY='D'; M= -31, -96, 79, 26, -97, -86, -74, -15, 22, -40, -85, -6, -84, 49, 8, -35, 2, -87,-103, -85; D=-24; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='R'; M= -14, 24, -78, -19, -84, -4, 36, -86, 34, -84, 40, -8, -11, 30, 54, 9, -76, -29, -90, 27; /M: SY='W'; M= -86, -92,-100, -92, 40, -99, 41, -9, -88, 60, 47, -94, -98, -85, -19, -91, -83, -18, 97, 13; /M: SY='L'; M= -31, -88, -18, -86, -65, -96, 19, -55, -23, 78, 37, -90, -1, -83, -86, -20, -77, -1, -92, -73; /M: SY='K'; M= 5, -90, -71, 34, -93, 1, 15, -88, 68, -90, -82, -9, -10, -65, -12, 10, 22, -12, -96, -84; /M: SY='P'; M= -8,-100, 40, 56, -98, -85, 8, -92, -34, -31, -86, -5, 95, -70, -81, -76, -76, -92,-100, -91; /M: SY='D'; M= -73, -90, 67, 9, -93, 49, -76, -95, -22, -95, -89, 16, -83, -72, -80, 28, 43, -90, -99, -3; /M: SY='G'; M= 24, 39, -85, -89, -90, 75, -90, -79, -86, -29, -80, -75, -13, -85, -92, -68, 26, 24, -96, -90; /M: SY='I'; M= -38, -91, -86, -22, -3, -93, -84, 56, 40, 7, 13, -18, -89, 6, 13, -8, -17, 19, -91, -75; /M: SY='M'; M= -29, 40, -94, -91, -7, -93, -91, 57, -88, -36, 59, -85, -91, -86, -91, 28, 7, 55, -96, -76; /M: SY='I'; M= -34, -91, -96, -15, 31, -98, -88, 73, -90, 13, 60, -91, -92, -86, -91, -15, -76, 14, 21, 13; /M: SY='P'; M= -84,-109, -84, -73,-104, -86, -87, -91, -80,-102, -88, -91, 131, -84, -93, -81, -76, -97, -97,-101; /M: SY='H'; M= 3, 51, 11, -72, -82, -80, 79, -90, -73, -87, -79, -67, -86, 40, -12, 53, 29, -85, -93, 41; /M: SY='S'; M= 17, -89, -79, -23, -14, -81, 27, -13, 47, -81, 35, -71, -84, -3, 23, 49, 3, -27, 37, -76; /M: SY='A'; M= 65, -7, -85, -85, -14, 52, -80, -82, -83, -83, -79, -77, -88, -80, -87, -20, -21, -17, -80, 63; /M: SY='T'; M= -37, -85, -22, -33, -84, -85, -82, 7, -70, -77, -75, -9, -84, -74, 43, 37, 76, 31,-101, -82; /M: SY='M'; M= -75, 11, -92, -88, -70, -92, -86, 44, -87, 47, 52, -84, -92, -5, -88, 45, -18, 22, -95, -76; /M: SY='Y'; M= -86, -97, -85, -81, 32, -93, 68, -78, 12, -74, -70, -80, -95, 7, -11, -38, -82, -32, 32, 111; /M: SY='A'; M= 49, 10, -94, -90, -75, 25, -90, 43, -89, 33, 30, -86, -91, -85, -91, -76, -76, 12, -93, -80; /M: SY='Q'; M= 40, 49, -85, -77, -82, -84, -83, -11, -19, -7, 43, -11, -89, 57, -79, -20, 17, 34, -97, -81; /M: SY='P'; M= 38, -95, -88, -78, -90, -38, -88, -75, -83, 3, -76, -89, 106, -84, -91, -76, -75, 12, -96, -92; /M: SY='I'; M= -30, -2, -97, -15, 22,-100, -95, 72, -90, -26, 45, -91, -92, -89, -93, -85, -20, 60, -92, -72; /M: SY='E'; M= -72, -90, -63, 76, -88, -38, -73, -87, 7, -84, 52, -7, -79, -2, -71, 47, 27, -84, -94, 3; /M: SY='S'; M= -13, 57, 34, -77, 54, -79, -80, -79, -32, -7, -78, 8, -90, -78, -83, 70, -67, -26, -91, -71; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='P'; M= -30, -99, 3, 5, -17, -32, -87, -83, -79, -11, -83, -82, 58, 21, 6, 21, 11, 4,-102, -89; D=-18; /I: I=-18; DM=-45; /M: SY='D'; M= -85, -99, 71, 34, -94, -92, -80, -27, 25, 15, -83, -13, -89, 10, -77, -7, -15, -87,-106, -88; D=-18; /I: I=-18; DM=-45; /M: SY='L'; M= -90, -96, -2, -24, 28,-104, 36, 4, -9, 63, -3, -92,-101, -86, -30, -94, -86, -69, -91, -13; D=-18; /I: I=-18; DM=-45; /M: SY='W'; M= -89,-103, -18, -81, 12, -42, 57, -87, -2, -23, 7, -83, -96, 40, 22, -85, -27, -91, 99, 66; D=-18; /I: I=-18; DM=-45; /M: SY='N'; M= 12, -96, -17, 42, -99, -85, -75, -27, 40, -96, -87, 61, -88, 3, 36, -21, -77, -91,-102, -90; D=-18; /I: I=-18; DM=-45; /M: SY='I'; M= -35, -93, 15, 29, -88, 20, 10, 41, -16, -81, -78, 14, 15, 24, -79, 30, -25, -26, 18, -82; /I: I=-10; MD=-25; /M: SY='R'; M= 9, -95, -82, -23, -86, -86, -78, -89, 9, 0, -81, 11, 12, -71, 58, 43, -75, -86, -93, 24; D=-10; /I: I=-10; MD=-25; /M: SY='S'; M= 33, 18, -93, -89, -21, -87, -91, 31, -86, -6, 32, -84, -93, -84, -20, 43, -7, 21, -99, -82; D=-10; /I: I=-10; MD=-25; /M: SY='P'; M= -18, 17, 24, -31, -93, -13, -84, -88, -24, -22, 6, 16, 62, 30, -85, 20, -78, -30, 58, -87; D=-10; /I: I=-10; MD=-25; /M: SY='F'; M= -83, 15, -23, -89, 56, 13, -85, -13, -87, 16, 9, -84, -97, 20, -20, 0, 8, -18, -84, 22; D=-10; /I: I=-10; MD=-25; /M: SY='W'; M= -85, 10, -94, -93, -81, 42, -98, -97, -15, -98, -94, 37, -97, -14, -91, -26, -91, -33, 140, -70; D=-10; /I: I=-10; MD=-25; /M: SY='S'; M= -79, -96, 51, 7,-102, -84, 4,-100, -73,-100, -93, 27, -19, 21, 10, 54, 26, -95,-110, -90; D=-10; /I: I=-10; MD=-25; /M: SY='C'; M= -80, 72, 36, -20, -99, -8, -85, -87, -24, -94, -89, 25, 22, 32, -86, 24, -77, 19,-110, -94; D=-10; /I: I=-10; MD=-25; /M: SY='V'; M= -47,-108,-110, -21, 4,-117,-109, -73,-106, 20, -82, -15,-116, -10,-108,-102, -22, 46,-115, -94; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='Y'; M= -34,-106, -17, 43, 28,-101, 32, -92, -87, -90, -88, -2,-101, -82, -90, -20, -89, -33, -82, 80; D=-10; /I: I=-10; DM=-25; /M: SY='G'; M= -82,-107, 8, -37,-111, 81, -97,-111, -95,-112,-103, -10, 13, -94,-103, -81, -94, -34,-107,-106; D=-10; /I: I=-10; DM=-25; /M: SY='F'; M= -93, 10, -21,-101, 80,-109,-101, 13, -21, -31, -76,-100, -16,-105,-100, -97, -88, 40, -87, -66; D=-10; /I: I=-10; DM=-25; /M: SY='D'; M= -91,-105, 92, -64,-106, -33, 8, -29, 0, -42, -96, 17, -94, 36, -82, -81, -84,-100,-117, -92; D=-10; /I: I=-10; DM=-25; /M: SY='M'; M= -83, -90,-102, -95, -68,-101, 19, -54, -93, 65, 89, -95, -99, -87, -91, -21, -80, 24, -97, -74; D=-10; /I: I=-10; DM=-25; /M: SY='S'; M= -72, -90, -77, -22, -93, -7, 13, -91, 2, -17, -85, 14, -5, -5, -7, 74, 23, -87,-102, -86; D=-10; /I: I=-10; DM=-25; /M: SY='C'; M= 20, 58, -16, 6, -4, -33, 10, -19, -76, 4, -74, -78, 31, -5, 8, 12, 13, 0, -96, -80; /M: SY='M'; M= 10, -86, -96, -90, 37, -93, 7, -6, -88, 50, 84, -89, -94, -84, -88, -25, -18, 4, -85, 1; /M: SY='D'; M= -80, -95, 58, -30, -16, 11, -77, 2, 36, -37, 8, 1, 47, -74, -23, -76, -22, -10, -91, 22; /M: SY='P'; M= -30, -96, 48, 15, 34, 24, -80, -92, 28, -90, -86, -71, 51, -4, -18, -32, 7, -90, 41, -77; /M: SY='M'; M= 10, -88, -86, 14, 39, -31, 8, 22, -34, 38, 57, -84, -16, -79, -85, 2, -8, -65, -87, -69; /M: SY='I'; M= 43, 12, -86, -22, 9, -85, 12, 46, 1, -24, -68, -80, -88, 21, -81, 5, -17, 25, -93, -76; /M: SY='H'; M= 21, -91, 25, -20, 11, 1, 73, -38, -2, -81, -5, -71, -86, 28, -76, 1, 7, 3, 41, -5; /M: SY='R'; M= -22, -96, 19, 18, -17, -88, -74, -27, 26, -87, -5, -72, 32, 50, 59, -20, 7, -85, -91, -4; /I: I=-10; MD=-25; /M: SY='C'; M= -30, 70, -27, 56, 12, 19, -98, -27, -91, -96, -96, -92,-100, -88, -98, -90, -92, -7,-108, -96; D=-10; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='Y'; M=-107,-121, -21, -24, 4, -50, -95,-109, -26,-106,-102,-102, -1, 20, -18, -99, 11,-109, -97, 60; D=-10; /I: I=-10; DM=-25; /M: SY='H'; M= 13,-104, -19, -21, 6,-100, 60, 13, -25, -31, -87, -89,-102, -90, -95, 11, 0, -86,-106, -6; D=-10; /I: I=-10; DM=-25; /M: SY='Y'; M= -2,-106, -93, -34, -94, -97, 21, -29, -35,-100, -93, -88, -2, 17, 20, 32, 6, -96,-101, 40; D=-10; /I: I=-10; DM=-25; /M: SY='E'; M= -88,-104, -87, 37, -99, -2, -95, -24, -26, -21, 5, -89, -25, 33, -90, -85, 35, 15,-110, -96; D=-10; /I: I=-10; DM=-25; /M: SY='P'; M= 3,-103, -8, -85, 17, -97, 5, -6, -6, -38, -83, -13, 61, 4, -19, -87, -85, 20,-102, -86; D=-10; /I: I=-10; DM=-25; /M: SY='Y'; M= 10, -96, -91, -87, -79, -93, 13, -31, -25, -13, 32, -11, -98, 26, -18, 10, -9, 22, -92, 49; D=-10; /I: I=-10; DM=-25; /M: SY='V'; M= -84, -98, 38, -83, -85, -98, -90, -28, -88, -13, 9, 16, -9, 26, -92, -25, -80, 58, 28, -3; D=-10; /I: I=-10; DM=-25; /M: SY='D'; M= 13, -95, 39, -11, -90, -21, 29, -88, -80, 4, -83, 13, -93, 11, -18, 36, -77, -28,-103, -3; D=-10; /I: I=-10; DM=-25; /M: SY='P'; M= -32, -98, -23, -22, -87, -44, -94, 24, 3, -9, -78, -87, 54, -85, -89, 20, -4, 25, 38, -88; D=-10; /I: I=-10; DM=-25; /M: SY='V'; M= -9, 22, -17, 2, 25, -99, -93, -6, -90, 4, -70, -92, 16, -90, -94, -85, -7, 59, -95, 1; D=-10; /I: I=-10; DM=-25; /M: SY='D'; M= -14, -96, 49, 23, -91, 19, 11, -23, 12, -31, -84, 30, 16, -73, -17, -34, -78, -19, -99, 0; D=-10; /I: I=-10; DM=-25; /M: SY='P'; M= 10, -98, -77, 32, 27, 1, -9, -33, -23, -90, -84, 15, 69, 32, -82, -22, -79, -88, -90, 3; D=-10; /I: I=-10; DM=-25; /M: SY='Q'; M= -85, 64, -15, 5, 12, -96, -79, -2, -34, -14, -77, -22, -95, 69, 29, -79, 7, -82, -90, 30; D=-10; /I: I=-10; DM=-25; /M: SY='Y'; M= -7, -96, 11, -75, -82, -87, 11, 19, 19, -38, -78, 9, 35, 12, 10, 20, -1, -79, -90, 42; D=-10; /I: I=-10; DM=-25; /M: SY='L'; M= -30, -2, -95, -20, -73, -99, 7, 15, -90, 55, -60, -93, 21, -5, -92, -22, -78, 43, -98, -79; D=-10; /I: I=-10; DM=-25; /M: SY='W'; M= -82, -91, -99, -92, -63, -95, -92, 11, -90, 64, 4, -18, -96, -86, -91, 1, -15, 5, 117, -65; /M: SY='S'; M= 23, -85, 11, 36, -94, -30, -77, -90, -71, -91, -85, -66, -80, 27, -77, 75, 39, -82, -99, -85; /M: SY='E'; M= -80, 22, 40, 59, -13, -88, -71, -92, 38, -88, -83, -71, -84, 18, 6, 0, -22, -89, 22, 57; /M: SY='P'; M= -21,-100, -81, -14, -97, -20, 9, -82, -79, -92, -83, -83, 111, 7, -87, 10, -74, 11, -98, -92; /M: SY='C'; M= -79, 64, -90, -87, 51, -22, 9, 28, -22, -31, 8, -6, -94, 13, -30, -24, -1, 29, 39, 9; /M: SY='P'; M= -31, -92, -31, 35, 28, -92, -82, 19, -2, -7, -72, -79, 44, 23, 7, -75, 35, 6, -91, -76; /M: SY='V'; M= -2, -88, -93, -88, 22, -94, 8, 32, -15, 34, 10, -12, 14, -85, -87, -82, -14, 47, -89, -9; /M: SY='F'; M= -17, -89, -91, -81, 73, -93, -81, -68, 48, 31, 54, -83, -92, -15, -15, -82, 2, -72, 42, -59; /I: I=-45; MD=-115; /M: SY='T'; M= -2, -94, -14, 40, -94, -2, 42, -92, 3, -30, -82, -72, -85, 28, 39, -21, 47, -87,-100, -84; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='F'; M= -81, -91, -8, -87, 78, -32, 12, 31, -88, 11, 27, -85, 13, 4, -88, 6, -77, 11, -80, -59; /M: SY='D'; M= -3, -94, 94, 19,-100, -81, -73, -94, 7, -96, -91, 28, 23, -69, -76, -19, -17, -31,-109, -88; /M: SY='F'; M= -84, 58, -93, -89, 81, -96, 55, -28, -88, 11, 27, -9, -97, 4, -87, -84, -18, 19, 35, -56; /M: SY='S'; M= -37, -92, -76, 9, -10, -82, 25, -84, -21, -21, 20, -9, 34, 43, 2, 53, -17, -84, 33, 41; /M: SY='T'; M= -75, -87, -75, -26, -84, -84, 9, -14, 36, -9, 54, 37, -84, 23, 2, 21, 60, -75, -98, -79; /M: SY='M'; M= 13, 7, -84, -21, -24, -88, 9, 16, 17, 20, 43, -8, 40, -5, 22, -22, -32, -34, -93, -78; /M: SY='Q'; M= -29, 24, -12, 19, -90, -41, -76, -18, 30, -83, 18, 36, -12, 48, -6, 20, 8, 11, -99, -84; /M: SY='E'; M= -12, -91, -5, 44, -4, -87, -81, 30, 19, -19, -74, -11, 13, -71, -16, 29, -11, 13, -95, -80; /M: SY='N'; M= -77, -90, 9, 24, -5, 6, 11, 0, -72, 1, -78, 75, -1, -7, -18, 29, -71, -82, -98, -80; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='D'; M= -80, -96, 84, 60, -99, -83, -71, -2, -68, -93, -89, 50, -4, 23, -76, -22, -73, -89,-107, -88; /M: SY='N'; M= -14, 18, -11, -80, 42, 12, -79, -1, 2, 16, -71, 46, -8, 7, 8, -77, -77, -10, -86, -1; /M: SY='S'; M= -29, -91, 36, 37, -4, -81, 2, -25, -29, -35, -81, -69, -9, -3, 13, 63, -16, -83, -91, 22; /I: I=-28; MD=-70; /M: SY='E'; M= -17,-111, -92, 30, 25, -24, -97,-103, 0,-102, -99, -94,-104, 19, 3, 1, -33, -23,-107, -93; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='R'; M= -42, 22, -94, -85, 26,-100, -89, -6, 31, -49, -86, -86,-101, 23, 42, 11, -18, -42, -96, -2; D=-28; /I: I=-28; DM=-70; /M: SY='C'; M= -79, 69, -17, 16, -5, -14, 20, -85, -82, -17, -84, -79, -94, -81, 0, 43, 23, 2,-105, -86; D=-28; /I: I=-28; DM=-70; /M: SY='K'; M= 5, -90, -11, 4, -15, 20, 9, -5, 37, -20, 20, 14, -84, 27, -71, 37, -26, -79, -94, -80; /M: SY='H'; M= -78, -93, 1, 28, -16, -89, 43, -25, 22, 2, -75, -74, 37, -3, 35, 17, 7, -7, -96, -78; /M: SY='F'; M= -77, 22, -87, -22, 54, 14, -86, 23, -81, -17, -70, -5, -22, -84, 5, 0, 24, 32, -86, -12; /M: SY='K'; M= -76, 23, -13, 41, -13, -88, 7, -82, 44, -16, -78, -71, -84, 25, 28, 25, 15, 0, -95, -79; /M: SY='F'; M= -31, 32, -95, -3, 72, -99, -91, 24, -90, 25, -62, -92, -14, -91, -92, -85, -19, 48, -83, -63; /M: SY='Q'; M= -76, -92, -24, 43, -15, -87, 32, -4, 6, -34, -75, 27, -10, 53, 0, 17, -17, 20, -97, -78; /M: SY='A'; M= 44, -3, -19, -32, 21, -86, 7, 40, -85, -4, 34, -16, -12, -82, -88, -31, 1, 24, -92, -74; /M: SY='S'; M= -13, 24, 29, -72, -82, -84, 36, 4, 19, -18, 26, -9, -9, -15, 20, 39, 7, -77, -94, 17; /M: SY='H'; M= -21, -92, -69, 29, -92, -13, 57, -91, 31, -88, 28, 35, -8, 23, 38, 2, 21, -88, -98, -80; /M: SY='S'; M= -12, 11, 15, -23, -91, -26, 4, -27, -74, -47, 18, 12, 55, -3, -13, 61, 13, -82,-100, -85; /M: SY='G'; M= 20, 11, -27, -22, -97, 82, -85, -98, -24, -96, -88, -68, -84, -78, -29, 9, 21, -90, -95, -91; /M: SY='Q'; M= -30, -91, 17, 7, -14, -88, -78, -22, -18, -6, -9, -73, 21, 44, 32, 6, 43, -1, -93, -15; /M: SY='C'; M= 7, 93, -95, -91, -11, -92, -89, 24, -90, 31, 28, -88, -12, -88, -92, 7, -74, 24, -94, -1; /M: SY='H'; M= -83, 34, 11, -19, -89, -84, 127, -96, -73, -86, 11, 49, -87, 21, -72, -72, 6, -94,-114, -66; /M: SY='G'; M= 55, 12, -84, -88, -94, 84, -89, -91, -85, -40, -84, -73, -86, -83, -91, -65, -79, -30, -93, -92; /M: SY='F'; M= -28, -88,-103, -97, 87,-100, -92, 47, -94, 10, 12, -94, -98, -96, -94, -88, -78, 46, -77, -56; /M: SY='A'; M= 62, -85, -89, -86, 11, 17, -90, 29, -85, 1, -69, -82, -1, -84, -90, -69, 22, 7, -91, -79; /M: SY='M'; M= -19, 11, -91, -91, 31, 47, -84, -4, -88, 33, 56, -81, -92, -84, -90, 15, -17, -16, -86, -2; /M: SY='W'; M= -92,-112,-110, -96, -1, -92, -93, -85, -88, -82, -83,-106, -98, -87, -90, -95, -98, -96, 168, 78; /M: SY='W'; M= -34, -93,-105, -98, 97, -97, -88, 8, -92, -61, 59, -96, -98, -95, -91, -90, -85, -16, 110, 15; /M: SY='D'; M= -30, -95, 100, 41,-100, -82, 23, -97, -19, -96, -92, -59, -82, -16, -76, 15, -73, -33,-111, -85; /M: SY='W'; M= -5, 13, -99, -92, -66, -94, -97, 37, -89, 13, -66, -92, -93, -88, -92, -25, 17, 48, 118, 3; /M: SY='H'; M= -36, 13, -15, 19, -83, -39, 83, -80, -72, -37, -74, -3, -86, 67, -74, -30, 30, 16, 36, 13; /M: SY='F'; M= -86, -88, -19, -93, 78,-100, -83, -7, -93, 62, 74, -94, -99, -90, -91, -92, -81, -61, -77, -56; /I: I=-7; MD=-17; /M: SY='D'; M= -24,-106, 81, -3,-111, -33, -89, -37, -86,-107,-103, -20, -27, -19, -94, -28, 27,-100,-122,-101; D=-7; /I: I=-7; MD=-17; /M: SY='G'; M= -25,-112, -19, 10,-116, 29, -98,-115, -9,-114, -9, -11, -14, -89, 5, 6, -25,-110,-117,-109; D=-7; /I: I=-7; MI=0; MD=-17; IM=0; DM=-17; /M: SY='Y'; M= -86,-103, -19, 47, -81, -94, 20, -35, -77, -93, -87, -11, -93, 31, -9, 30, -19, -93, -87, 70; D=-7; /I: I=-7; DM=-17; /M: SY='N'; M= -77, -95, 6, 9, -97, 38, -76, -92, 55, -95, -2, 58, 54, -8, -68, -71, -75, -32, -97, -89; /M: SY='D'; M= -3, -92, 46, 40, -95, -20, -77, -88, 17, -49, -84, -3, 30, -4, 7, 10, 32, -28,-100, -87; /M: SY='I'; M= -76, 39, -91, -89, -11, -96, 8, 63, -85, -4, -62, -13, -92, -19, -20, -14, 33, 49, -97, -75; /M: SY='W'; M= -75, 11, -83, 0, 29, -15, 36, -10, -24, -12, 12, -1, -89, -80, -83, 21, 23, 44, 59, -70; /M: SY='L'; M= -84, 11,-102, -96, 18,-103, -87, 39, -95, 76, 14, -98, -99, -90, -93, -92, -79, -11, -85, -3; /M: SY='S'; M= -62, -82, 17, -73, -92, -26, -78, -90, -75, -93, -87, -61, -81, -69, -80, 100, 44, -82,-102, -84; /M: SY='T'; M= -71, 39, -81, -83, -81, -87, -86, 37, -79, -72, 34, -70, -81, -80, -86, 21, 99, -62,-102, -81; /M: SY='G'; M= 48, -88, -14, 19, -94, 66, -81, -91, -79, -34, 7, 16, -84, -75, -85, 15, -74, -85, -95, -89; /M: SY='P'; M= -82,-106, -85, -74, -97, -86, -87, -86, -81, -10, -83, -90, 125, -83, -92, -13, -75, -91, -96, -97; /M: SY='S'; M= -29, -90, 18, 20, 18, -6, -75, -79, -4, 22, -74, -4, -87, 11, -19, 39, 3, -79, -85, 36; /M: SY='W'; M= -1, -91, 38, 40, -85, -32, 21, -88, -74, -89, -85, 22, -83, -71, -80, 24, 49, -29, 102, -75; /I: I=-11; MD=-28; /M: SY='P'; M= 17, -95, -85, -31, -14, -29, 37, 4, 5, -84, 8, -79, 60, -10, 7, -17, 32, -28, -98, -83; D=-11; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='H'; M= -21, -94, 26, -20, -92, -89, 63, -25, -38, -44, -82, -10, 22, -80, -86, 21, 49, 15,-111, -85; D=-11; /I: I=-11; DM=-28; /M: SY='P'; M= -79, 6, -17, -21, -97, -89, -88, -84, -23, -92, -86, -9, 67, -5, -87, 19, 66, 3,-108, -93; D=-11; /I: I=-11; DM=-28; /M: SY='N'; M= -27,-118, 8, 38,-123, 9, -97,-123, -91,-122,-114, 41, -2, -90, -16, -94, -99,-119,-125,-115; D=-11; /I: I=-11; DM=-28; /M: SY='M'; M= -37,-113,-110,-110, -16, 16, 7, -96,-107, -14, 73, -15, -15,-102,-109, -3,-100, -99,-116, -98; D=-11; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='D'; M= -99,-110, 44, -92, 26,-107,-100, -97, -17, -97, 40, -90, -10, -99,-101, 5, 21, -29,-114, -93; D=-11; /I: I=-11; DM=-28; /M: SY='H'; M= -79, 12, -74, -75, 18, -20, 124, -94, -77, -84, -75, 16, -89, -3, -75, 38, -76, -93, -95, 34; /M: SY='W'; M= -90, 14,-115, -96, -59, -91,-111, -86, -89, -86, -88,-107, -97, -89, -92, -28, -98, -22, 175, 13; /M: SY='K'; M= -39, -93, -81, -19, 40, -8, -2, -83, 73, -78, 62, -74, -87, -67, 28, -18, -78, -83, 35, 20; /M: SY='Q'; M= -78,-103, -74, -55, -18, -85, -68, -92, -61, -89, -77, -71, 55, 126, -63, -69, -79, -94, -89, -79; /M: SY='C'; M= 52, 54, -87, -85, -87, 44, -90, 37, -84, -78, -75, -78, -11, -11, -90, -68, 28, -5, -96, -87; /M: SY='V'; M= -19, -87, -98, -92, -12, -99, -91, 33, -87, 9, 10, -93, -96, -88, 1, -84, -73, 81, -91, 25; /M: SY='Y'; M= -87, 34, -91, -86, 71, -96, 57, -19, -18, 10, 10, -85, -97, 27, -80, -85, -83, -75, 34, 80; /M: SY='F'; M= -85, -92, -96, -90, 67, -97, -81, -22, -90, 43, -2, -94, 62, -90, -91, -87, -27, 4, -74, 53; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='L'; M= -7, -88, -94, -89, 36, -94, -84, 10, -87, 66, 28, -3, 14, -85, -20, -24, -77, -21, -86, -69; /M: SY='P'; M= -77, -97, 10, 16, -99, 15, -77, -96, 40, -97, -87, -21, 71, 12, 34, 19, -17, -93, -96, -89; /M: SY='Q'; M= -78, -94, 49, 26, -96, -30, -72, -92, 58, -40, -83, 12, -82, 62, -13, -26, 27, -89, -98, -84; /M: SY='P'; M= -80,-103, -79, 4,-100, -31, -83, -90, 17, -97, -86, -82, 113, -1, -21, -14, -17, -42, -96, -94; /M: SY='I'; M= -77, -90, -92, -24, -27, -32, -90, 53, -24, 21, 11, -87, 13, -84, 8, -82, 19, 50, -95, -77; /M: SY='C'; M= -27, 65, -76, 29, 5, -87, -77, -83, 8, -36, -79, -15, 46, 14, -14, 15, 21, -27, -87, 40; /M: SY='V'; M= -36, -87, -8, -24, 32, -99, -92, 1, -89, 36, -60, -92, -96, -6, -90, -85, -75, 74, 34, -70; /M: SY='H'; M= -12, -2, -76, 12, -86, -26, 53, -19, 5, -7, 8, 0, -10, 20, 29, 36, -15, -4, -98, -79; /M: SY='E'; M= 15, -92, -8, 53, -94, -26, -75, -86, 16, -86, 38, 17, 32, 29, 14, -20, 1, -29, -97, -86; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='G'; M= -36, -92, 31, -82, 47, 78, -82, -93, -83, -90, -87, 32, -7, -83, -89, -69, 6, -91, -89, -77; /M: SY='Q'; M= -76, -93, 61, 28, -97, -82, -72, -91, 10, -92, -85, 18, -4, 63, -12, 27, 29, -31,-102, -85; /M: SY='P'; M= -15, -91, 4, 26, -93, -83, -77, -35, 21, -88, -82, 31, 49, 22, 8, 6, 47, -16, -99, -86; /M: SY='I'; M= -78, -89, -96, -92, 29, -97, -87, 54, -87, 42, -58, -89, -95, -86, -9, 24, -74, 35, -84, 24; /M: SY='S'; M= -72, -87, -71, 35, -79, -82, 8, -77, 13, 8, -75, 30, -84, -69, -74, 54, 43, -4, -93, 23; /I: I=-12; MD=-29; /M: SY='G'; M= -7, -94, -94, -97, 12, 65, -92, 18, -93, 14, -74, -84, -95, -91, -97, -24, -83, 13, -90, 1; D=-12; /I: I=-12; MD=-29; /M: SY='H'; M= -28, -98, 16, 44, -99, -6, 52, -98, 14, -36, -87, 10, -87, 21, -17, -11, 27, -93,-106, -87; D=-12; /I: I=-12; MD=-29; /M: SY='I'; M= -34, 54,-108,-103, 11,-107,-100, 56,-100, 15, 50,-100,-103, -98,-101, -94, -82, 39, -99, -79; D=-12; /I: I=-12; MD=-29; /M: SY='W'; M= -31,-100, -13, -18, -90, -90, 8, -92, -5, -23, -87, 39, -95, 31, -17, 24, 16, -42, 80, -4; D=-12; /I: I=-12; MD=-29; /M: SY='F'; M= -30,-101,-109,-102, 79,-109, -95, -22, -90, 3, 3,-100,-109, -98, 35, -96, -22, -4, -87, -66; D=-12; /I: I=-12; MD=-29; /M: SY='C'; M= -88, 54, -94, -90, -97, -97, 29, 13, -89, -23, -88, -1,-103, 41, -21, 47, -84, -89, 36, -91; D=-12; /I: I=-12; MD=-29; /M: SY='F'; M= -16, 8,-102, -96, 34,-106, 14,-103, -11, -37, -95, -1, -2, 14, 16, -17, -97,-103,-103, -5; D=-12; /I: I=-12; MD=-29; /M: SY='N'; M= -96,-111, 11, -97, -20, -97, 7,-118, -98,-120,-113, 57,-112, -94,-103, 52, -88,-115,-129,-105; D=-12; /I: I=-12; MI=0; MD=-29; IM=0; DM=-29; /M: SY='L'; M= -38,-119,-116,-107,-101, -19, 4, -95, -6, 40, -87,-111,-121, 25,-104,-109,-109, -99,-120,-103; D=-12; /I: I=-12; DM=-29; /M: SY='Q'; M= -90,-107, -13, -34,-104,-103, -93, -36, 39, -95, -90, -29,-101, 49, -8, 2, -22, 30,-112, -97; D=-12; /I: I=-12; DM=-29; /M: SY='S'; M= -9, 55, 22, -6, -17, 13, -84, -93, -78, -93, -89, -71, -7, -77, 2, 61, 22, -40,-103, -88; /M: SY='N'; M= -31, 12, 37, -14, -88, -40, 36, -92, 18, -22, -84, 53, -90, -11, -4, 15, 12, -90, -99, 23; /M: SY='H'; M= -76, -92, -78, -31, -94, -85, 73, -91, -76, -92, -85, -10, 16, 1, 2, 53, 64, -39,-109, -82; /M: SY='D'; M= -84, 22, 53, 36, -15, -4, -81, -3, 46, -91, -87, -73, -89, 25, -20, -80, -82, -29, -98, -12; /M: SY='D'; M= -39, 12, 63, 18, -89, -31, -5, -21, -14, 0, -79, -76, -92, -80, -86, 4, -32, 37,-109, -87; /M: SY='W'; M= -91,-103,-104,-100, 34,-100, -84, 25, -94, -13, 33, -98,-103, -91, -94, 9, -88, -76, 105, 80; /M: SY='Y'; M= -21, 10, -87, 5, -79, -41, 10, -22, -35, -38, -84, -14, -25, -82, -19, 39, -19, -4, -90, 62; /M: SY='M'; M= -91,-101, -92, 40, -82,-109, -91, 7, -89, 30, 65, -97, -99, -85, -20, -93, 4, -4,-102, -3; /M: SY='W'; M= -95,-115, -95, 22, -84,-100, 14, -99, -25, -41, -94, -18,-100, 32, -7, -28, -98, -41, 136, -72; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 147 in 116 different sequences |
| Number of true positive hits | 147 in 116 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Feature key [info] | DOMAIN |
| Feature description [info] | SAM-dependent MTase PRMT-type |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
116 sequences
ANM10_ARATH (Q9MAT5), ANM10_ORYSI (A2Y953), ANM10_ORYSJ (Q9SNQ2), ANM11_ARATH (Q9SU94), ANM12_ARATH (O82210), ANM13_ARATH (Q84W92), ANM14_ARATH (A3KPF2), ANM15_ARATH (Q8GWT4), ANM16_ARATH (Q944R7), ANM1A_XENLA (Q8AV13), ANM1B_XENLA (Q6VRB0), ANM1_CAEEL (Q9U2X0), ANM1_CHLRE (A8IEF3), ANM1_DICDI (Q54EF2), ANM1_HUMAN (Q99873), ANM1_MOUSE (Q9JIF0), ANM1_ORYSI (A2Z0C0), ANM1_ORYSJ (Q0J2C6), ANM1_RAT(Q63009), ANM1_SCHPO (Q9URX7), ANM1_XENTR (Q28F07), ANM2_DICDI (Q54HI0), ANM2_HUMAN (P55345), ANM2_MOUSE (Q9R144), ANM2_XENLA (D9IVE5), ANM2_XENTR (B3DLB3), ANM3_ARATH (Q0WVD6), ANM3_HUMAN (O60678), ANM3_MOUSE (Q922H1), ANM3_ORYSI (A2YP56), ANM3_ORYSJ (A3BMN9), ANM3_RAT(O70467), ANM3_SCHPO (O13648), ANM5_BOVIN (A7YW45), ANM5_CAEEL (P46580), ANM5_DICDI (Q54KI3), ANM5_DROME (Q9U6Y9), ANM5_HUMAN (O14744), ANM5_MACFA (Q4R5M3), ANM5_MOUSE (Q8CIG8), ANM5_ORYSI (A2X0Q3), ANM5_ORYSJ (Q6YXZ7), ANM5_PONAB (Q5R698), ANM5_XENLA (Q6NUA1), ANM61_ORYSI (A2XYY8), ANM61_ORYSJ (Q7XKC0), ANM62_ORYSI (A2Z8S0), ANM62_ORYSJ (Q75G68), ANM6_ARATH (Q08A71), ANM6_BOVIN (Q5E9L5), ANM6_DANRE (Q6NWG4), ANM6_HUMAN (Q96LA8), ANM6_MOUSE (Q6NZB1), ANM6_XENLA (Q68EZ3), ANM6_XENTR (B0JYW5), ANM7_AEDAE (Q16NS8), ANM7_ANOGA (Q7QIL2), ANM7_BOVIN (A6QQV6), ANM7_CAEBR (A8XFF4), ANM7_CAEEL (Q9XW42), ANM7_CHICK (Q5ZIB9), ANM7_CRILO (Q99MI9), ANM7_CULQU (B0X4N1), ANM7_DANRE (A2AV36), ANM7_DROAN (B3MF31), ANM7_DROER (B3NP10), ANM7_DROGR (B4JWL5), ANM7_DROME (Q9W1V1), ANM7_DROMO (B4KSL6), ANM7_DROPE (B4GA28), ANM7_DROPS (B5DZN7), ANM7_DROSE (B4I8G2), ANM7_DROSI (B4QI55), ANM7_DROVI (B4LPB6), ANM7_DROWI (B4MNL1), ANM7_DROYA (B4P925), ANM7_HUMAN (Q9NVM4), ANM7_MOUSE (Q922X9), ANM7_ORYSI (A2Y8B9), ANM7_ORYSJ (Q5VS72), ANM7_RAT(Q5U4E8), ANM7_TRYB2 (Q582G4), ANM7_XENLA (Q6PCI6), ANM8B_DANRE (Q5RGQ2), ANM8_HUMAN (Q9NR22), ANM8_MOUSE (Q6PAK3), ANM9_HUMAN (Q6P2P2), ANM9_MOUSE (Q3U3W5), ANM9_XENLA (A0JMU5), CARM1_AEDAE (Q174R2), CARM1_ANOGA (Q7Q2B7), CARM1_CULQU (B0W3L6), CARM1_DANRE (Q6DC04), CARM1_DROAN (B3M1E1), CARM1_DROER (B3P4N5), CARM1_DROGR (B4JXV2), CARM1_DROME (Q9VH48), CARM1_DROMO (B4KA23), CARM1_DROPE (B4GZ20), CARM1_DROPS (Q29B63), CARM1_DROSE (B4HJC0), CARM1_DROSI (B4QVW6), CARM1_DROVI (B4LVS8), CARM1_DROWI (B4NKI9), CARM1_DROYA (B4PVH6), CARM1_HUMAN (Q86X55), CARM1_MOUSE (Q9WVG6), CARM1_ORYSI (A2YPT7), CARM1_ORYSJ (Q7XI75), CARM1_RAT (Q4AE70), CARM1_SCHMA (A0A3Q0KHE7), CARM1_XENLA (Q5XK84), HMT1_YEAST (P38074), HSL7_YEAST (P38274), SKB1_SCHPO (P78963), SZNE_STRC2 (A0A411EW25)» more
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| PDB [Detailed view] |
183 PDB
1F3L; 1G6Q; 1OR8; 1ORH; 1ORI; 2FYT; 2V74; 2V7E; 2Y1W; 2Y1X; 3B3F; 3B3G; 3B3J; 3Q7E; 3R0Q; 3SMQ; 3UA3; 3UA4; 3WST; 3X0D; 4C03; 4C04; 4C05; 4C06; 4C07; 4C08; 4C4A; 4G56; 4GQB; 4HC4; 4HSG; 4IKP; 4M36; 4M37; 4M38; 4QPP; 4QQK; 4QQN; 4RYL; 4X41; 4X60; 4X61; 4X63; 4Y2H; 4Y30; 5C9Z; 5DST; 5DWQ; 5DX0; 5DX1; 5DX8; 5DXA; 5DXJ; 5E8R; 5EGS; 5EMJ; 5EMK; 5EML; 5EMM; 5FA5; 5FQN; 5FQO; 5HZM; 5IH3; 5IS6; 5IS7; 5IS8; 5IS9; 5ISA; 5ISB; 5ISC; 5ISD; 5ISE; 5ISF; 5ISG; 5ISH; 5ISI; 5K8V; 5K8W; 5K8X; 5LGP; 5LGQ; 5LGR; 5LGS; 5LKJ; 5LV2; 5LV3; 5LV4; 5LV5; 5NTC; 5TBH; 5TBI; 5TBJ; 5U4X; 5WCF; 6ARJ; 6ARV; 6CKC; 6D2L; 6DVR; 6IZQ; 6K1S; 6NT2; 6OGN; 6P7I; 6PDM; 6RLL; 6RLQ; 6S70; 6S71; 6S74; 6S77; 6S79; 6S7A; 6S7B; 6S7C; 6SQ3; 6SQ4; 6SQH; 6SQI; 6SQK; 6UGH; 6UXX; 6UXY; 6V0N; 6V0O; 6V0P; 6W6D; 6WAD; 7BO7; 7FAI; 7FAJ; 7KIB; 7KIC; 7KID; 7L1G; 7M05; 7MX7; 7MXA; 7MXC; 7MXG; 7MXN; 7NR4; 7NUD; 7NUE; 7OKP; 7OS4; 7P2R; 7PPQ; 7PPY; 7PU8; 7PUC; 7PUQ; 7PV6; 7QPH; 7QRD; 7RBQ; 7S0U; 7S1P; 7S1Q; 7S1R; 7S1S; 7SER; 7SES; 7T39; 7U30; 7U9I; 7UOH; 7UY1; 7UYF; 7ZUP; 7ZUQ; 7ZUU; 7ZUY; 7ZV2; 7ZVL; 7ZVU; 8CSG; 8CTB; 8CYI; 8G1U; 8G2F; 8G2G » more |