PROSITE entry PS00246

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General information about the entry

Entry name [info]	WNT1
Accession [info]	PS00246
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00219

Name and characterization of the entry

Description [info]	Wnt-1 family signature.
Pattern [info]	C-[KR]-C-H-G-[LIVMT]-S-G-x-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	135 in 135 different sequences
Number of true positive hits	135 in 135 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	59

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

135 sequences

LIN44_CAEBR (A8XEH1), LIN44_CAEEL (Q27886), MOM2_CAEEL  (Q10459),

W11B1_XENTR (Q66II0), W11B2_XENTR (Q28J82), WN10A_DANRE (P43446), 
WN10A_HUMAN (Q9GZT5), WN10A_MOUSE (P70701), WN10B_DANRE (Q801F7), 
WN10B_HUMAN (O00744), WN10B_MOUSE (P48614), WN11B_XENLA (P49893), 
WN2BA_XENLA (P87387), WNT10_XENLA (P31292), WNT11_CHICK (P49339), 
WNT11_COTJA (P51891), WNT11_DANRE (O73864), WNT11_HUMAN (O96014), 
WNT11_MOUSE (P48615), WNT11_XENLA (Q670P5), WNT11_XENTR (B2GUT4), 
WNT16_BOVIN (Q5E9U6), WNT16_HUMAN (Q9UBV4), WNT16_MOUSE (Q9QYS1), 
WNT1_AMBME  (P21551), WNT1_BOMMO  (P49340), WNT1_CAEEL  (P34888), 
WNT1_CHICK  (Q91029), WNT1_DANRE  (P24257), WNT1_HUMAN  (P04628), 
WNT1_MOUSE  (P04426), WNT1_STRPU  (P28094), WNT1_XENLA  (P10108), 
WNT2B_CHICK (Q98SN7), WNT2B_HUMAN (Q93097), WNT2B_MOUSE (O70283), 
WNT2_AOTNA  (Q07DV4), WNT2_ATEGE  (Q09YK7), WNT2_BOVIN  (A4D7S0), 
WNT2_CAEEL  (P34889), WNT2_CALJA  (Q2QLG1), WNT2_CARPS  (Q2QLC7), 
WNT2_CHLAE  (Q2IBB0), WNT2_COLGU  (Q07DY7), WNT2_DANRE  (Q92048), 
WNT2_DASNO  (Q07E44), WNT2_DIDVI  (Q2QL76), WNT2_DROME  (P28465), 
WNT2_ECHTE  (A1X153), WNT2_EULMM  (Q2IBG1), WNT2_FELCA  (A0M8T2), 
WNT2_GORGO  (Q2IBF4), WNT2_HORSE  (Q2QLA5), WNT2_HUMAN  (P09544), 
WNT2_LOXAF  (Q108U2), WNT2_MICMU  (Q2QL85), WNT2_MONDO  (Q2QL96), 
WNT2_MOUSE  (P21552), WNT2_MUNMU  (Q09YJ6), WNT2_MUNRE  (Q07DW8), 
WNT2_MUSPF  (Q07E18), WNT2_NEONE  (Q07E31), WNT2_NOMLE  (Q07DX7), 
WNT2_ORNAN  (Q07DZ8), WNT2_OTOGA  (Q2QLH2), WNT2_PANTR  (Q2QLE7), 
WNT2_PAPAN  (A0M8S1), WNT2_PLEMO  (Q2QLB6), WNT2_PONAB  (Q2IBE2), 
WNT2_RABIT  (Q09YN1), WNT2_RHIFE  (Q2IBB5), WNT2_SHEEP  (Q09YI4), 
WNT3A_CHICK (Q2LMP1), WNT3A_HUMAN (P56704), WNT3A_MOUSE (P27467), 
WNT3A_XENLA (P31285), WNT3_HUMAN  (P56703), WNT3_MOUSE  (P17553), 
WNT3_XENLA  (P31284), WNT4A_DANRE (P47793), WNT4_CHICK  (P49337), 
WNT4_DROME  (P40589), WNT4_HUMAN  (P56705), WNT4_MOUSE  (P22724), 
WNT4_RAT(Q9QXQ5), WNT4_XENLA  (P49338), WNT5A_AMBME (Q06442), 
WNT5A_HUMAN (P41221), WNT5A_MOUSE (P22725), WNT5A_PLEWA (O13267), 
WNT5A_RABIT (Q27Q52), WNT5A_RAT   (Q9QXQ7), WNT5A_XENLA (P31286), 
WNT5B_AMBME (Q06443), WNT5B_DANRE (Q92050), WNT5B_HUMAN (Q9H1J7), 
WNT5B_MOUSE (P22726), WNT5B_ORYLA (O42122), WNT5B_PONAB (Q5NVK2), 
WNT5B_XENLA (P33945), WNT5_DROME  (P28466), WNT5_HALRO  (O15978), 
WNT6_HUMAN  (Q9Y6F9), WNT6_MOUSE  (P22727), WNT6_XENLA  (P31287), 
WNT7A_AOTTR (Q1KYK4), WNT7A_CALJA (Q1KYK6), WNT7A_CHLAE (Q1KYL3), 
WNT7A_GORGO (Q1KYK7), WNT7A_HUMAN (O00755), WNT7A_MACFA (Q1KYK9), 
WNT7A_MOUSE (P24383), WNT7A_PANTR (Q1KYL1), WNT7A_PONPY (Q1KYK5), 
WNT7A_XENLA (P31288), WNT7B_CHICK (Q3L254), WNT7B_HUMAN (P56706), 
WNT7B_MOUSE (P28047), WNT7B_XENLA (P31289), WNT7C_XENLA (P31290), 
WNT8A_DANRE (P51028), WNT8A_HUMAN (Q9H1J5), WNT8A_MOUSE (Q64527), 
WNT8B_DANRE (P51029), WNT8B_HUMAN (Q93098), WNT8B_MOUSE (Q9WUD6), 
WNT8B_XENLA (P31291), WNT8C_CHICK (P51030), WNT8_XENLA  (P28026), 
WNT9A_CHICK (O42280), WNT9A_HUMAN (O14904), WNT9A_MOUSE (Q8R5M2), 
WNT9B_HUMAN (O14905), WNT9B_MOUSE (O35468), WNTG_DROME  (P09615)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
'Partial' sequences

59 sequences

WN10A_ALOVU (P28099), WN10A_PLEJO (P28131), WN10B_PLEJO (P28132),

WN2BB_XENLA (P31283), WNT10_EPTST (P28112), WNT1_ALOVU  (P28100), 
WNT1_EVATR  (P28089), WNT1_PITME  (P28139), WNT1_PLESK  (P28113), 
WNT1_SCEOC  (P28141), WNT2_STRPU  (P28095), WNT3A_ALOVU (P28101), 
WNT3A_MELGA (P28125), WNT3A_PITME (P28140), WNT3A_PLEJO (P28133), 
WNT3A_SCEOC (P28142), WNT3B_ALOVU (P28102), WNT3B_MELGA (P28126), 
WNT3B_PLEJO (P28134), WNT3_EPTST  (P28114), WNT3_EVATR  (P28090), 
WNT4_ANSCE  (P28108), WNT4_EPTST  (P28115), WNT4_MELGA  (P28127), 
WNT4_PLEJO  (P28135), WNT4_PLESK  (P28116), WNT4_SCEOC  (P28143), 
WNT4_STRPU  (P28096), WNT51_EPTST (P28119), WNT52_EPTST (P28120), 
WNT53_EPTST (P28121), WNT5A_ALOVU (P28103), WNT5A_ANSCE (P28109), 
WNT5A_MELGA (P28128), WNT5A_PLESK (P28117), WNT5B_ALOVU (P28104), 
WNT5B_PLEJO (P28136), WNT5B_PLESK (P28118), WNT6_EVATR  (P28091), 
WNT6_PLEJO  (P28137), WNT6_STRPU  (P28097), WNT6_THUTH  (P28145), 
WNT71_EPTST (P28122), WNT72_EPTST (P28123), WNT7A_ALOVU (P28105), 
WNT7A_ANSCE (P28110), WNT7A_MELGA (P28129), WNT7A_PLEJO (P28138), 
WNT7B_ALOVU (P28106), WNT7B_ANSCE (P28111), WNT7B_MELGA (P28130), 
WNT7B_SCEOC (P28144), WNT7_EVATR  (P28092), WNT7_STRPU  (P28098), 
WNT8_EVATR  (P28093), WNT8_THUTH  (P28146), WNT9_ALOVU  (P28107), 
WNT9_EPTST  (P28124), WNTG_MANSE  (Q25533)

» more

PDB
[Detailed view]

9 PDB

4F0A; 6AHY; 7DRT; 7KC4; 7URD; 8CTG; 8TZO; 8TZP; 8TZR