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NiceZyme View of ENZYME: EC 1.1.1.50

Accepted Name
3-alpha-hydroxysteroid dehydrogenase (B-specific).
Alternative Name(s)
3-alpha-HSD.
Hydroxyprostaglandin dehydrogenase.
Reaction catalysed
Androsterone + NAD(P)(+) <=> 5-alpha-androstane-3,17-dione + NAD(P)H
Comment(s)
  • Acts on other 3-alpha-hydroxysteroids and on 9-, 11- and 15-hydroxyprostaglandin.
  • B-specific with respect to NAD(+) or NADP(+) (cf. EC 1.1.1.213).
Cross-references
Biochemical Pathways; map number(s)F9 ; G9 ; G10 ; I10 ; J9 ; K9 ; L9 ; L10
PROSITEPDOC00061
BRENDA1.1.1.50
EC2PDB1.1.1.50
PRIAM enzyme-specific profiles1.1.1.50
KEGG Ligand Database for Enzyme Nomenclature1.1.1.50
IUBMB Enzyme Nomenclature1.1.1.50
IntEnz1.1.1.50
MEDLINEFind literature relating to 1.1.1.50
MetaCyc1.1.1.50
UniProtKB/Swiss-Prot
P17516, AK1C4_HUMAN;  Q95JH5, AK1C4_MACFA;  Q95JH4, AK1C4_MACFU;  
P80702, DIDH_COMTE;  P80701, DIDH_PSESP;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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